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SPRY1 Knockout Cell Lines

Gene: SPRY1

Official Full Name: sprouty RTK signaling antagonist 1provided by HGNC

Gene Summary: Involved in negative regulation of fibroblast growth factor receptor signaling pathway. Located in Golgi apparatus; cytosol; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO32075 SPRY1 Knockout cell line (HCT 116) Human SPRY1 1:2~1:4 Negative Online Inquiry
KO32076 SPRY1 Knockout cell line (HEK293) Human SPRY1 1:3~1:6 Negative Online Inquiry

Background

SPRY1 Gene Knockout Cell Lines are specialized cellular models engineered to lack the SPRY1 gene, which plays a vital role in various signaling pathways associated with cell proliferation, differentiation, and development. By utilizing CRISPR-Cas9 gene-editing technology, these cell lines allow for precise and efficient deletion of the SPRY1 gene. This targeted approach offers researchers an invaluable tool for studying the downstream effects of SPRY1 loss, facilitating insights into cellular mechanisms pertinent to both normal physiology and disease states.

The primary function of SPRY1 involves its regulatory capacity over receptor tyrosine kinases and associated signaling pathways, such as MAPK/ERK and PI3K/AKT. The knockout of this gene can significantly enhance or alter signaling cascades, providing a versatile platform for researchers investigating processes like cancer progression, neurodevelopmental disorders, and stem cell biology. Additionally, these knockout cell lines serve as essential models for drug discovery, enabling the identification of potential therapeutic targets and the development of strategies to combat diseases linked to SPRY1 dysregulation.

What sets our SPRY1 Gene Knockout Cell Lines apart from alternatives is their unparalleled specificity and reliability. The optimized knockout process ensures consistent performance across different clones, offering reproducible and reliable data for experiments. Furthermore, these cell lines are compatible with a wide range of assays, including cell viability, migration, and gene expression analyses, making them applicable to diverse research areas.

Researchers and clinicians will find tremendous value in utilizing SPRY1 Gene Knockout Cell Lines for their projects, as they not only accelerate the exploration of fundamental biological questions but also contribute to the development of novel therapeutic strategies. This product represents a significant advancement in cell line technology, paving the way for groundbreaking discoveries.

As a company deeply committed to advancing scientific research, we pride ourselves on our expertise in genetic engineering and cell line production. Our rigorous quality control and validation processes ensure that researchers receive high-quality resources that drive innovation and contribute to the broader field of biomedical research.

Please note that all services are for research use only. Not intended for any clinical use.

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