Gene: SPRED2
Official Full Name: sprouty related EVH1 domain containing 2provided by HGNC
Gene Summary: SPRED2 is a member of the Sprouty (see SPRY1; MIM 602465)/SPRED family of proteins that regulate growth factor-induced activation of the MAP kinase cascade (see MAPK1; MIM 176948) (Nonami et al., 2004 [PubMed 15465815]).[supplied by OMIM, Mar 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO37896 | SPRED2 Knockout cell line (HeLa) | Human | SPRED2 | 1:3~1:6 | Negative | Online Inquiry |
KO37897 | SPRED2 Knockout cell line (HCT 116) | Human | SPRED2 | 1:2~1:4 | Negative | Online Inquiry |
KO37898 | SPRED2 Knockout cell line (HEK293) | Human | SPRED2 | 1:3~1:6 | Negative | Online Inquiry |
KO37899 | SPRED2 Knockout cell line (A549) | Human | SPRED2 | 1:3~1:4 | Negative | Online Inquiry |
SPRED2 Gene Knockout Cell Lines are genetically engineered cell lines that facilitate the targeted disruption of the SPRED2 gene, which encodes a critical scaffold protein involved in cellular signaling pathways, particularly those related to the Ras-MAPK cascade. These knockout cell lines serve as a powerful tool for researchers investigating the role of SPRED2 in various biological processes, including cell growth, differentiation, and oncogenesis.
The primary mechanism of action in SPRED2 gene knockout cell lines involves the use of CRISPR-Cas9 technology or other gene-editing techniques to selectively inactivate the SPRED2 gene, thereby enabling scientists to study the resultant phenotypic changes compared to wild-type cell lines. By observing these changes under controlled experimental conditions, researchers can elucidate the functional contributions of SPRED2 in signal transduction pathways and its implications in diseases such as cancer and developmental disorders.
In the scientific community, SPRED2 gene knockout cell lines are invaluable in both basic and translational research. Their application extends to drug discovery, where insights gained from these cell lines can inform the development of targeted therapies. Moreover, they serve as reference models for the investigation of gene function and regulation, aiding in the identification of novel therapeutic targets.
What sets our SPRED2 gene knockout cell lines apart is their high efficiency and specificity in gene editing, coupled with comprehensive validation measures to ensure reliability and reproducibility in experimental outcomes. Additionally, these cell lines are compatible with a variety of assay formats, enhancing their versatility for diverse research applications.
For researchers, clinicians, and biotechnology companies, SPRED2 gene knockout cell lines represent a cutting-edge resource, enabling groundbreaking discoveries and innovative solutions in gene function analysis and therapeutic development. Our company, with its commitment to quality and innovation in genetic tools, provides these state-of-the-art products that empower the scientific community to explore new frontiers in biology.
Please note that all services are for research use only. Not intended for any clinical use.
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