Gene: SPOCK3
Official Full Name: SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3provided by HGNC
Gene Summary: This gene encodes a member of a novel family of calcium-binding proteoglycan proteins that contain thyroglobulin type-1 and Kazal-like domains. The encoded protein and may play a role in adult T-cell leukemia by inhibiting the activity of membrane-type matrix metalloproteinases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO23271 | SPOCK3 Knockout cell line (HeLa) | Human | SPOCK3 | 1:3~1:6 | Negative | Online Inquiry |
SPOCK3 Gene Knockout Cell Lines represent a cutting-edge tool in the field of genetic research and therapeutics. These cell lines have been engineered to possess a targeted knockout of the SPOCK3 gene, which encodes a protein involved in various physiological and pathological processes, particularly in cellular adhesion, migration, and tissue integrity. By creating a specific gene disruption, researchers can elucidate the functional role of SPOCK3 in diverse biological contexts, allowing for a deeper understanding of its contributions to cellular dynamics.
The primary mechanism by which SPOCK3 Gene Knockout Cell Lines function is through the complete inactivation of the SPOCK3 gene, utilizing advanced gene-editing technologies such as CRISPR-Cas9 or other homologous recombination techniques. This knockout model enables the investigation of downstream signaling pathways and gene interactions that are otherwise obscured by the presence of the functional protein. Consequently, researchers are equipped to study a breadth of conditions, including cancer, fibrosis, and neurodegeneration.
The scientific significance of these cell lines extends to both basic research and clinical applications. They serve as invaluable models in drug discovery, enabling the screening of potential therapeutic agents that may target SPOCK3-related pathways. Furthermore, they provide insights into gene function that can facilitate the development of gene therapies designed to restore normal function in disease states.
A key advantage of the SPOCK3 Gene Knockout Cell Lines is their potential for precision and reproducibility in experimental outcomes, compared to other gene manipulation techniques, which might yield inconsistent results. These cell lines allow for the establishment of stable and homogenous populations that are essential for high-throughput screening and detailed mechanistic studies.
For researchers and clinicians seeking to advance their understanding of gene function and its implications in disease, the SPOCK3 Gene Knockout Cell Lines are an indispensable resource. Our company, specializing in innovative biological products, is committed to providing top-tier genomic tools that empower the scientific community in their quest for breakthrough discoveries. With our expertise and rigorous quality standards, we ensure that our products meet the highest benchmarks for research excellence.
Please note that all services are for research use only. Not intended for any clinical use.
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