Gene: SPOCK2
Official Full Name: SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2provided by HGNC
Gene Summary: This gene encodes a protein which binds with glycosaminoglycans to form part of the extracellular matrix. The protein contains thyroglobulin type-1, follistatin-like, and calcium-binding domains, and has glycosaminoglycan attachment sites in the acidic C-terminal region. Three alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Oct 2011]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO32729 | SPOCK2 Knockout cell line (HEK293) | Human | SPOCK2 | 1:3~1:6 | Negative | Online Inquiry |
SPOCK2 Gene Knockout Cell Lines are genetically modified cell lines in which the SPOCK2 gene has been inactivated, allowing researchers to investigate the functional role of this gene in various biological processes. The SPOCK2 gene encodes a protein involved in the regulation of cell adhesion, proliferation, and migration, making these knockout models critical for elucidating the underlying mechanisms of numerous physiological and pathological conditions, including cancer metastasis and tissue remodeling.
These cell lines operate by utilizing CRISPR-Cas9 technology to precisely disrupt the SPOCK2 gene. The knockout effect leads to the absence of the protein product, enabling comparative studies to measure changes in cellular behavior and gene expression profiles in response to the gene's inactivation. This phenotypic alteration is pivotal for gaining insights into cellular pathways and the biological impacts of SPOCK2.
From a scientific perspective, the availability of SPOCK2 Gene Knockout Cell Lines significantly enhances research efforts aimed at understanding the gene's involvement in development, disease progression, and potential therapeutic targets. They serve as essential tools for both basic research in cell biology and translational applications in clinical settings.
What sets these cell lines apart from alternatives is their rigorously validated knockout efficiency, coupled with the comprehensive characterization of the resulting cellular phenotypes. Users benefit from a consistent and reproducible model that can save valuable time and resources while yielding high-quality data.
Researchers, clinicians, and biotech companies will find tremendous value in the insights gained from these knockout models, empowering them to pioneer investigations that could lead to novel treatments or diagnostic techniques. Our company specializes in providing expertly designed biological products, ensuring that our offerings meet the highest standards of quality and scientific integrity, thus supporting your research endeavors effectively.
Please note that all services are for research use only. Not intended for any clinical use.
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