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SPINDOC Knockout Cell Lines

Gene: SPINDOC

Official Full Name: spindlin interactor and repressor of chromatin bindingprovided by HGNC

Gene Summary: Involved in DNA damage response and negative regulation of DNA-templated transcription. Is active in nucleus and site of DNA damage. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO24144 SPINDOC Knockout cell line (HeLa) Human SPINDOC 1:3~1:6 Negative Online Inquiry
KO24145 SPINDOC Knockout cell line (HCT 116) Human SPINDOC 1:2~1:4 Negative Online Inquiry
KO24146 SPINDOC Knockout cell line (HEK293) Human SPINDOC 1:3~1:6 Negative Online Inquiry
KO24147 SPINDOC Knockout cell line (A549) Human SPINDOC 1:3~1:4 Negative Online Inquiry

Background

SPINDOC Gene Knockout Cell Lines are specialized cellular models engineered to facilitate gene function studies by selectively disrupting the expression of target genes. These cell lines utilize precise gene editing technologies, such as CRISPR-Cas9, to introduce targeted mutations, thereby enabling researchers to investigate the role of specific genes in various biological processes.

The key mechanism behind SPINDOC Gene Knockout Cell Lines lies in their ability to enable phenotype characterization upon gene disruption. By employing this innovative approach, researchers can discern the functional relevance of genes, elucidating pathways involved in cellular behaviors such as proliferation, differentiation, and response to pharmacological interventions. This advanced modeling is pivotal not only for fundamental biological research but also for applications in drug discovery and development, where understanding gene function can lead to the identification of novel therapeutic targets.

The scientific importance of SPINDOC Gene Knockout Cell Lines is underscored by their broad applicability across numerous fields, including cancer research, genetic disorders, and regenerative medicine. In clinical settings, these cell lines can expedite translational research, allowing for the rapid generation of data regarding gene-drug interactions and disease mechanisms.

What sets SPINDOC Gene Knockout Cell Lines apart from conventional alternatives is their customization and optimization for specific research objectives, combined with a streamlined validation process that ensures high reliability and reproducibility of results. Furthermore, these cell lines offer significant time-saving advantages for researchers who seek to explore gene functions without the complexities associated with traditional gene knockout models.

By choosing SPINDOC Gene Knockout Cell Lines, researchers and clinicians can harness state-of-the-art genetic engineering to unlock valuable insights, driving forward their research agendas and enhancing the development of innovative therapies. Our company prides itself on delivering high-quality biological products, backed by a commitment to scientific excellence and customer support, ensuring that our users are equipped with tools that empower their groundbreaking work in biomedical research.

Please note that all services are for research use only. Not intended for any clinical use.

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