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SPIN2A Knockout Cell Lines

Gene: SPIN2A

Official Full Name: spindlin family member 2Aprovided by HGNC

Gene Summary: This gene encodes one of three members of the DXF34 gene family, located in a 100-kb region of chromosome Xp11.21. [provided by RefSeq, Nov 2009]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO21748 SPIN2A Knockout cell line (HeLa) Human SPIN2A 1:3~1:6 Negative Online Inquiry

Background

SPIN2A Gene Knockout Cell Lines represent a cutting-edge biological research tool specifically designed for investigating the role of the SPIN2A gene in cellular processes. These cell lines are engineered using CRISPR-Cas9 technology to induce precise mutations that disrupt the SPIN2A gene function. This results in a lack of expression of the protein associated with the gene, allowing researchers to study its effects on cell behavior, signaling pathways, and overall physiological functions.

Key mechanisms of these knockout cell lines involve targeted gene editing, which effectively creates a loss-of-function model. By analyzing cellular responses in the absence of SPIN2A, researchers can deduce its biological significance, including its potential involvement in processes such as cell proliferation, apoptosis, and differentiation. The ability to observe these phenomena in vitro provides invaluable insights that may directly translate to therapeutic developments or disease understanding.

The scientific importance of SPIN2A Gene Knockout Cell Lines is underscored by their applications across numerous research disciplines, including oncology, neurology, and developmental biology. Their use is particularly relevant for elucidating mechanisms behind SPIN2A-related disorders, thereby paving the way for innovative approaches in drug discovery and target validation.

One of the remarkable advantages of using SPIN2A Gene Knockout Cell Lines is the high specificity and efficiency of the CRISPR-Cas9 technique, which reduces off-target effects common in previous gene editing methods. Additionally, these cell lines are readily adaptable for high-throughput screening, facilitating accelerated research timelines compared to traditional methods.

For researchers and clinicians, the value of SPIN2A Gene Knockout Cell Lines lies in their ability to provide a clear understanding of gene function while offering a reliable platform for deliverables in translational research. Moreover, our commitment to quality and precision in developing these lines is backed by extensive expertise in gene editing technologies, ensuring that you receive the highest standard of biological products tailored for your research needs.

Please note that all services are for research use only. Not intended for any clinical use.

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