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SPATA2L Knockout Cell Lines

Gene: SPATA2L

Official Full Name: spermatogenesis associated 2 likeprovided by HGNC

Gene Summary: Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO28269 SPATA2L Knockout cell line (HeLa) Human SPATA2L 1:3~1:6 Negative Online Inquiry
KO28270 SPATA2L Knockout cell line (HCT 116) Human SPATA2L 1:2~1:4 Negative Online Inquiry
KO28271 SPATA2L Knockout cell line (HEK293) Human SPATA2L 1:3~1:6 Negative Online Inquiry
KO28272 SPATA2L Knockout cell line (A549) Human SPATA2L 1:3~1:4 Negative Online Inquiry

Background

SPATA2L Gene Knockout Cell Lines are engineered cellular systems specifically designed to facilitate the understanding of the SPATA2L gene's role in cellular processes and disease mechanisms. Utilizing the CRISPR/Cas9 gene-editing technology, these cell lines have the SPATA2L gene precisely disrupted, enabling the study of its functional consequences in various biological contexts, including reproductive biology, cancer research, and stress response mechanisms.

The primary function of the SPATA2L gene is linked to sperm motility and fertility, positioning these knockout cell lines as invaluable tools for elucidating reproductive biology. The underlying mechanism involves the gene’s contribution to flagellar structure and function during sperm development, thereby affecting motility. By employing these cell lines, researchers can dissect cellular pathways and identify downstream effects of SPATA2L disruptions, enhancing our understanding of fertility-related conditions.

The scientific importance of SPATA2L knockout cell lines extends into various research and clinical applications, especially in studying infertility and associated pathologies. Furthermore, they are pivotal in drug discovery and therapeutic developments aimed at ameliorating reproductive dysfunctions. Their versatility enables integration into various experimental setups, providing a robust platform for investigating gene function, interactions, and compensatory mechanisms.

Compared to alternative systems such as standard wild-type cell lines or less specific gene editing techniques, SPATA2L knockout cell lines offer precise alterations with a clear genetic basis. This specificity leads to more reliable and reproducible data, promoting confidence in research outcomes. Additionally, the ease of use and the capacity for high-throughput analyses position these cell lines as a superior choice for busy laboratories.

For researchers and clinicians dedicated to unraveling the complexities of human genetics and improving patient outcomes in reproductive health, SPATA2L Gene Knockout Cell Lines represent an exceptional resource. Our company has extensive expertise in producing high-quality biological products and stands committed to supporting the scientific community with innovative solutions that drive forward breakthroughs in research.

Please note that all services are for research use only. Not intended for any clinical use.

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