Gene: SPANXN4
Official Full Name: SPANX family member N4provided by HGNC
Gene Summary: This gene represents one of several duplicated family members that are located on the X chromosome. This gene family encodes proteins that play a role in spermiogenesis. These proteins represent a specific subgroup of cancer/testis-associated antigens, and they may be candidates for tumor vaccines. This family member belongs to a subgroup of related genes that are present in all primates and rats and mice, and thus, it represents one of the ancestral family members. [provided by RefSeq, Sep 2009]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO13825 | SPANXN4 Knockout cell line (HeLa) | Human | SPANXN4 | 1:3~1:6 | Negative | Online Inquiry |
SPANXN4 Gene Knockout Cell Lines are specifically engineered cellular models designed to facilitate the study of the SPANXN4 gene's function and its implications in various biological processes and diseases. Utilizing CRISPR-Cas9 technology, these cell lines provide a precise and efficient way to create targeted gene knockouts, allowing researchers to disrupt the SPANXN4 gene and observe the resultant phenotypic and molecular changes. This targeted approach enables an enhanced understanding of gene function, signaling pathways, and potential therapeutic targets.
The key mechanism involves the introduction of a double-strand break at the SPANXN4 locus through the CRISPR-Cas9 system, leading to insertions or deletions (indels) that result in a frameshift mutation. This mutation effectively silences the gene, making it an essential tool for dissecting its role in cellular dynamics, particularly in cancer biology and reproductive health. Understanding the biological processes influenced by SPANXN4 is critical, as it has been implicated in tumorigenesis and other pathologies.
These knockout cell lines hold significant value in both research and clinical settings. Their application spans fundamental biology studies, drug discovery, and the development of gene therapies. The ability to model diseases in vitro using SPANXN4 knockout cells accelerates the discovery of novel therapeutic approaches by providing insights into disease mechanisms that may not be accessible in vivo.
One of the unique selling points of SPANXN4 Gene Knockout Cell Lines is their reproducibility and ease of use. Unlike alternative methods that offer lower precision or require extensive validation, these cell lines are rigorously validated for functionality, ensuring consistent results across different experiments. This reliability saves researchers time and resources, ultimately expediting their discovery efforts.
For researchers and clinicians, the SPANXN4 Gene Knockout Cell Lines represent an invaluable resource that not only deepens our understanding of gene function but also empowers innovative therapeutic strategies. By leveraging our expertise in genetic engineering and cellular biology, our company is committed to providing high-quality biological products that drive advancements in scientific research and healthcare solutions.
Please note that all services are for research use only. Not intended for any clinical use.
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