Gene: SP110
Official Full Name: SP110 nuclear body proteinprovided by HGNC
Gene Summary: The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. This gene is a member of the SP100/SP140 family of nuclear body proteins and encodes a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. In addition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction of myeloid cell differentiation. Alternative splicing has been observed for this gene and three transcript variants, encoding distinct isoforms, have been identified. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO37113 | SP110 Knockout cell line (HeLa) | Human | SP110 | 1:3~1:6 | Negative | Online Inquiry |
KO37114 | SP110 Knockout cell line (HCT 116) | Human | SP110 | 1:2~1:4 | Negative | Online Inquiry |
KO37115 | SP110 Knockout cell line (HEK293) | Human | SP110 | 1:3~1:6 | Negative | Online Inquiry |
KO37116 | SP110 Knockout cell line (A549) | Human | SP110 | 1:3~1:4 | Negative | Online Inquiry |
SP110 Gene Knockout Cell Lines are sophisticated biological tools developed for advanced genetic studies and functional research. These cell lines are engineered to have a targeted deletion of the SP110 gene, a component implicated in various cellular processes including immune response and cellular differentiation. By completely knocking out this gene, researchers can investigate the resultant phenotypic changes and gain insights into the underlying biological mechanisms.
The primary function of SP110 Gene Knockout Cell Lines lies in their ability to facilitate comprehensive studies in gene function and regulation, particularly in the context of diseases where the SP110 gene may play a key role. These cell lines exhibit altered expression profiles and cellular pathways, thus providing a unique platform for exploring genetic interactions, disease mechanisms, and therapeutic targets. By employing CRISPR/Cas9 technology to achieve precise gene editing, these cell lines allow for reproducible and robust experimentation.
Scientifically, SP110 Gene Knockout Cell Lines offer significant applications in research settings, particularly in immunology and oncology. They enable researchers to dissect the functional implications of SP110 in immune cell behavior and response to pathogens, making them invaluable for studying autoimmune diseases and cancer immunotherapy.
Compared to traditional cell lines, the SP110 Gene Knockout Cell Lines present unique advantages such as a higher degree of specificity and efficiency in gene targeting, allowing for more accurate experimental outcomes. Furthermore, they are validated for consistent performance in high-throughput screening, ensuring reliability in experimental designs.
For researchers and clinicians alike, the availability of SP110 Gene Knockout Cell Lines means access to cutting-edge tools that can accelerate discoveries and enhance understanding of complex biological systems. The value lies not just in the results they yield, but in the broader implications for therapeutic development and precision medicine.
Our company prides itself on a strong commitment to innovation in genetic research, developing high-quality biological products that empower the scientific community. With an expertise in genetic engineering and a thorough understanding of cellular biology, we are dedicated to providing our customers with the best tools to propel their research forward.
Please note that all services are for research use only. Not intended for any clinical use.
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