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SOX17 Knockout Cell Lines

Gene: SOX17

Official Full Name: SRY-box transcription factor 17provided by HGNC

Gene Summary: This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO11668 SOX17 Knockout cell line (HeLa) Human SOX17 1:3~1:6 Negative Online Inquiry

Background

SOX17 Gene Knockout Cell Lines are engineered cellular models specifically designed to facilitate the study of the role of the SOX17 gene in various biological processes. These cell lines have been created through precise genome editing techniques, enabling the targeted deletion of the SOX17 gene, which is known to be critical for embryonic development, stem cell differentiation, and tissue homeostasis. By eliminating this gene, researchers can investigate its functions and the consequent cellular pathways that are affected, offering insights into developmental biology and disease mechanisms.

The primary mechanism of these knockout cell lines involves the CRISPR-Cas9 or similar gene-editing technologies, which introduce specific double-strand breaks in the DNA, leading to the disruption of the SOX17 gene. This targeted approach allows scientists to generate a stable model system that mimics the loss-of-function scenarios that are often observed in pathological conditions. The resultant cell lines provide a robust platform for in vitro studies related to cell differentiation, organoid formation, and even disease modeling in conditions such as cancer and cardiovascular diseases.

The scientific importance of SOX17 Gene Knockout Cell Lines cannot be overstated. They serve as an invaluable tool in both fundamental and translational research settings, enabling high-throughput screening of compounds that may modulate SOX17-related pathways. Furthermore, they can be utilized for understanding the underlying genetic mechanisms that contribute to diverse pathologies, thereby accelerating the development of targeted therapies.

What sets these knockout cell lines apart from alternatives is their reliable and reproducible nature, combined with a comprehensive validation of the gene knockout status. Researchers can be confident that the studies performed with these cell lines are consistent and reflective of true biological alterations. Additionally, the user-friendly maintenance and handling protocols minimize prior technical knowledge, facilitating a wider adoption amongst researchers in various domains.

The value of SOX17 Gene Knockout Cell Lines extends beyond mere laboratory use; they provide a critical link between basic research findings and potential clinical applications. The derived insights can pave the way for innovative treatments, and their role in elucidating gene function places them at the forefront of genetic research.

At [Your Company Name], we pride ourselves on our commitment to delivering high-quality biological products that empower researchers and clinicians alike. Our expertise in genetic engineering ensures that every product, including the SOX17 Gene Knockout Cell Lines, meets stringent standards of quality and reliability, fostering advancements in scientific discovery and therapeutic development.

Please note that all services are for research use only. Not intended for any clinical use.

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