Gene: SOX11
Official Full Name: SRY-box transcription factor 11provided by HGNC
Gene Summary: This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may function in the developing nervous system and play a role in tumorigenesis. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO04965 | SOX11 Knockout cell line (HEK293) | Human | SOX11 | 1:3~1:6 | Negative | Online Inquiry |
SOX11 Gene Knockout Cell Lines are innovative research tools specifically engineered to silence the SOX11 gene, a transcription factor implicated in various biological processes, including development and oncogenesis. This product utilizes CRISPR-Cas9 technology to precisely edit the genomic sequence, creating a complete knockout of the SOX11 gene. The resulting cell lines serve as powerful platforms to investigate the effects of SOX11 deficiency on cellular behavior, differentiation, and tumorigenesis.
The primary mechanism of action involves the introduction of double-strand breaks at the SOX11 locus, followed by the cell's repair processes, which can lead to frameshift mutations that disrupt the gene's normal expression. This targeted gene disruption allows researchers to elucidate the role of SOX11 in cancer metastasis and other diseases, thereby providing insights critical to both fundamental biology and therapeutic innovation.
The scientific importance of SOX11 Gene Knockout Cell Lines is underscored by their applications in cancer research, particularly in understanding hematological malignancies where SOX11 has been shown to drive tumor progression. These cell lines are crucial for drug discovery efforts, enabling researchers to test the efficacy of targeted therapies and study the underlying molecular mechanisms linked to SOX11's activity.
In comparison to traditional gene silencing methods, such as RNA interference, the SOX11 Gene Knockout Cell Lines provide a more permanent and stable means of gene inactivation. This durability ensures consistency in experiments, thereby yielding reliable data and enhancing reproducibility. Furthermore, the versatility of these cell lines allows for their utilization across various cell types, making them indispensable for numerous research applications.
For researchers and clinicians, the value of SOX11 Gene Knockout Cell Lines lies in their capability to advance our understanding of complex biological systems and facilitate the development of innovative treatment strategies. With the growing focus on personalized medicine, understanding the nuanced roles of transcription factors like SOX11 could lead to more effective interventions for patients.
Our company specializes in providing high-quality, customizable biological products tailored to meet the needs of modern research. With expertise in gene editing and a commitment to scientific innovation, we deliver reliable tools that empower researchers to make significant strides in their work.
Please note that all services are for research use only. Not intended for any clinical use.
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CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.