Gene: SOSTDC1
Official Full Name: sclerostin domain containing 1provided by HGNC
Gene Summary: This gene is a member of the sclerostin family and encodes an N-glycosylated, secreted protein with a C-terminal cystine knot-like domain. This protein functions as a bone morphogenetic protein (BMP) antagonist. Specifically, it directly associates with BMPs, prohibiting them from binding their receptors, thereby regulating BMP signaling during cellular proliferation, differentiation, and programmed cell death. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO28622 | SOSTDC1 Knockout cell line (HEK293) | Human | SOSTDC1 | 1:3~1:6 | Negative | Online Inquiry |
SOSTDC1 Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to study the functions of the SOSTDC1 gene, which encodes a protein with significant roles in bone density regulation and certain signaling pathways. By leveraging CRISPR-Cas9 gene-editing technology, these cell lines have been meticulously developed to provide a reliable model for examining the physiological and pathological implications of SOSTDC1 deficiency, facilitating researchers' understanding of skeletal development and disease.
The primary function of SOSTDC1 lies in its ability to modulate the Wnt and bone morphogenetic protein (BMP) signaling pathways, which are critical for bone formation and homeostasis. The knockout of SOSTDC1 allows for the dissection of these pathways, revealing insights into the gene’s function in osteoblast differentiation and proliferation. Moreover, utilizing these knockout cell lines enables the investigation of SOSTDC1 in various disease contexts, such as osteoporosis and craniofacial anomalies, thereby accelerating the development of targeted therapeutic strategies.
From a scientific perspective, SOSTDC1 Gene Knockout Cell Lines serve invaluable purposes in both research and clinical settings. Their implementation in studies investigating bone biology enables scientists to understand intricate molecular interactions, making them essential for drug discovery and the development of advanced biomaterials.
One significant advantage of using our SOSTDC1 knockout cell lines is their specificity and reproducibility. Unlike traditional methods, which may yield inconsistent results across different studies, our cell lines provide a controlled environment, ensuring consistent experimental outcomes. Furthermore, they are designed for ease of use and compatibility with various assays, making them ideal for both high-throughput applications and in-depth molecular analyses.
Researchers and clinicians are increasingly driven to incorporate these cell lines into their work owing to their capability to advance our understanding of bone biology, enabling the exploration of novel therapeutic avenues. This product stands as a testament to the importance of innovative gene-editing tools in modern biological research.
With years of experience in developing cutting-edge biological products, our company is committed to providing high-quality research tools that empower the scientific community. The SOSTDC1 Gene Knockout Cell Lines exemplify our dedication to supporting breakthroughs in cellular and molecular biology.
Please note that all services are for research use only. Not intended for any clinical use.
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