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SORBS3 Knockout Cell Lines

Gene: SORBS3

Official Full Name: sorbin and SH3 domain containing 3provided by HGNC

Gene Summary: This gene encodes an SH3 domain-containing adaptor protein. The presence of SH3 domains play a role in this protein's ability to bind other cytoplasmic molecules and contribute to cystoskeletal organization, cell adhesion and migration, signaling, and gene expression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO32196 SORBS3 Knockout cell line (HeLa) Human SORBS3 1:3~1:6 Negative Online Inquiry
KO32197 SORBS3 Knockout cell line (HCT 116) Human SORBS3 1:2~1:4 Negative Online Inquiry
KO32198 SORBS3 Knockout cell line (HEK293) Human SORBS3 1:3~1:6 Negative Online Inquiry
KO32199 SORBS3 Knockout cell line (A549) Human SORBS3 1:3~1:4 Negative Online Inquiry

Background

SORBS3 Gene Knockout Cell Lines are specialized cellular models designed to facilitate comprehensive studies of the SORBS3 gene and its associated biological pathways. These cell lines have been engineered using precise CRISPR/Cas9 gene editing techniques to eliminate the SORBS3 gene, a crucial component involved in diverse cellular functions, including glucose metabolism, adipogenesis, and insulin signaling pathways. By providing a systemically modified counterpart to wild-type cells, SORBS3 knockout lines enable researchers to dissect gene function and explore the implications of SORBS3 deficiency in various conditions, such as metabolic disorders and obesity.

The key functionality of these knockout cell lines lies in their ability to serve as a reliable platform for experimental validation of gene function, molecular mechanisms, and therapeutic targets. By blocking the expression of SORBS3, researchers can study the resulting phenotypic changes and cellular behaviors, which may elucidate the gene's role in pathophysiological contexts. This capability is especially valuable in translational research, allowing for the exploration of potential interventions in metabolic disease management.

The scientific importance of SORBS3 Gene Knockout Cell Lines extends into both research and clinical fields. These cell lines have prominent applications in drug discovery, genetic interaction studies, and therapeutic development, contributing to our understanding of metabolic syndrome and related conditions. They can also provide insights into the mechanisms of action for novel therapies targeting insulin resistance and obesity.

One distinctive advantage of SORBS3 Gene Knockout Cell Lines over traditional models is the precision and reliability achieved through advanced gene editing technologies, allowing for reproducible experiments and reduced variability. Additionally, these knockout lines offer a cost-effective approach to screening and characterizing compounds, streamlining research workflows.

For researchers, clinicians, and pharmaceutical developers, SORBS3 Gene Knockout Cell Lines represent an indispensable tool that stands at the intersection of cutting-edge science and translational potential. Leveraging these cell lines can accelerate advancements in understanding disease mechanisms and developing innovative treatments. Our company is dedicated to delivering high-quality biological products backed by extensive expertise in genetic engineering and cellular biology, ensuring that our customers receive reliable tools to drive their research forward.

Please note that all services are for research use only. Not intended for any clinical use.

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