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SNX9 Knockout Cell Lines

Gene: SNX9

Official Full Name: sorting nexin 9provided by HGNC

Gene Summary: This gene encodes a member of the sorting nexin family. Members of this family contain a phosphoinositide binding domain, and are involved in intracellular trafficking. The encoded protein does not contain a coiled coil region, like some family members, but does contain a SRC homology domain near its N-terminus. The encoded protein is reported to have a variety of interaction partners, including of adaptor protein 2 , dynamin, tyrosine kinase non-receptor 2, Wiskott-Aldrich syndrome-like, and ARP3 actin-related protein 3. The encoded protein is implicated in several stages of intracellular trafficking, including endocytosis, macropinocytosis, and F-actin nucleation. [provided by RefSeq, Jul 2013]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO04060 SNX9 Knockout cell line (HeLa) Human SNX9 1:3~1:6 Negative Online Inquiry
KO04061 SNX9 Knockout cell line (HCT 116) Human SNX9 1:2~1:4 Negative Online Inquiry
KO04062 SNX9 Knockout cell line (HEK293) Human SNX9 1:3~1:6 Negative Online Inquiry
KO04063 SNX9 Knockout cell line (A549) Human SNX9 1:3~1:4 Negative Online Inquiry

Background

SNX9 Gene Knockout Cell Lines are genetically modified cell lines designed to facilitate in-depth studies of the SNX9 gene, which is a critical component in the regulation of endocytosis and the sorting of proteins within cells. These cell lines have been engineered to contain targeted deletions of the SNX9 gene, allowing researchers to investigate the gene's function, its associated protein interactions, and its role in various cellular pathways.

The primary function of SNX9 involves cargo recognition and membrane remodeling during the endocytic process, which is essential for cellular homeostasis and the modulation of signaling pathways. By utilizing SNX9 Gene Knockout Cell Lines, researchers can better understand the mechanistic details of endocytosis and its implications in health and disease, including neurodegenerative disorders, cancer, and infectious diseases. The absence of SNX9 provides a unique opportunity to elucidate compensatory mechanisms and the involvement of other cellular proteins in these critical biological processes.

Scientifically, these cell lines are invaluable for both basic and applied research. In clinical settings, the insights gained from studying SNX9's role can inform therapies aimed at modulating endocytic pathways for enhanced drug delivery or the targeting of tumor cells. Compared to alternative gene knockout models, our SNX9 Cell Lines offer superior specificity, ensured through precise CRISPR-Cas9 technology, minimizing off-target effects and maintaining the integrity of surrounding genes.

The value of SNX9 Gene Knockout Cell Lines extends beyond their genetic modifications; they are indispensable tools for researchers aiming to dissect molecular mechanisms, develop therapeutic strategies, and translate basic research into clinical applications. Our extensive expertise in genetic engineering and commitment to quality ensure that these cell lines provide reliable and reproducible results to advance your research endeavors. Choose our SNX9 Gene Knockout Cell Lines to enrich your investigations into the critical roles of endocytic pathways in cellular biology.

Please note that all services are for research use only. Not intended for any clinical use.

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