Gene: SNX8
Official Full Name: sorting nexin 8provided by HGNC
Gene Summary: Enables identical protein binding activity and phosphatidylinositol binding activity. Involved in early endosome to Golgi transport and intracellular protein transport. Located in early endosome membrane and retromer complex. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO27006 | SNX8 Knockout cell line (HeLa) | Human | SNX8 | 1:3~1:6 | Negative | Online Inquiry |
KO27007 | SNX8 Knockout cell line (HCT 116) | Human | SNX8 | 1:2~1:4 | Negative | Online Inquiry |
KO27008 | SNX8 Knockout cell line (HEK293) | Human | SNX8 | 1:3~1:6 | Negative | Online Inquiry |
KO27009 | SNX8 Knockout cell line (A549) | Human | SNX8 | 1:3~1:4 | Negative | Online Inquiry |
SNX8 Gene Knockout Cell Lines are genetically engineered cell lines that have been specifically designed to lack the expression of the Sorting Nexin 8 (SNX8) gene. This innovative product allows researchers to investigate the functional implications of SNX8 deficiency in cellular processes such as endosomal trafficking, cellular signaling, and protein sorting. By precisely knocking out the SNX8 gene, these cell lines provide a robust model for understanding the gene's role in various physiological and pathological conditions.
The key function of SNX8 Knockout Cell Lines centers around their capability to elucidate the mechanisms of endosomal dynamics and cargo recycling pathways that are critical for maintaining cellular homeostasis. Researchers can leverage these cell lines to observe firsthand the bioenergetic shifts, changes in protein expression profiles, and alterations in endocytosis rates that occur due to the absence of SNX8. This enables a more profound understanding of diseases that may be linked to dysfunctional endosomal processing, such as neurodegeneration and cancer.
In clinical and research settings, the SNX8 Gene Knockout Cell Lines offer significant applications, particularly in drug discovery and metabolic studies. They serve as invaluable tools for drug testing and development, helping to identify potential therapeutic targets for drug-resistant cancers or to assess the cellular response to new pharmacological compounds.
Compared to alternative models, our SNX8 Knockout Cell Lines are engineered using cutting-edge CRISPR/Cas9 technology, ensuring high precision and reproducibility. Unlike traditional knockout methods, our product minimizes off-target effects and enhances the reliability of experimental outcomes, providing researchers with a dependable resource for their investigations.
This product is particularly valuable for researchers and clinicians seeking to elucidate the complexities of cellular pathways or developing targeted therapies. The ability to manipulate gene expression with specificity opens a myriad of possibilities for studies on cell physiology, disease mechanisms, and therapeutic interventions.
Our company is dedicated to advancing the field of genetic research through high-quality biological products backed by extensive expertise in genetic engineering and cell line development. We are committed to supporting the scientific community with tools that effectively drive innovation and discovery.
Please note that all services are for research use only. Not intended for any clinical use.
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