Gene: SNX30
Official Full Name: sorting nexin family member 30provided by HGNC
Gene Summary: Predicted to enable phosphatidylinositol binding activity. Involved in positive regulation of autophagosome assembly and protein transport. Is active in early endosome. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO21345 | SNX30 Knockout cell line (HeLa) | Human | SNX30 | 1:3~1:6 | Negative | Online Inquiry |
KO21346 | SNX30 Knockout cell line (HCT 116) | Human | SNX30 | 1:2~1:4 | Negative | Online Inquiry |
KO21347 | SNX30 Knockout cell line (HEK293) | Human | SNX30 | 1:3~1:6 | Negative | Online Inquiry |
KO21348 | SNX30 Knockout cell line (A549) | Human | SNX30 | 1:3~1:4 | Negative | Online Inquiry |
SNX30 Gene Knockout Cell Lines are engineered cellular models characterized by the interruption of the SNX30 gene, which encodes for a sorting nexin protein involved in intracellular trafficking and membrane dynamics. These knockout cell lines are generated through advanced gene-editing techniques such as CRISPR-Cas9, ensuring precise alterations to the genomic sequence. The primary function of SNX30 is to facilitate the endosomal sorting of proteins and lipids, thereby influencing cellular homeostasis and signaling pathways. The absence of this gene allows researchers to elucidate its specific roles in cellular processes, including endosome recycling, autophagy, and response to extracellular stimuli.
These cell lines serve as invaluable tools in both research and clinical settings, particularly in the study of metabolic diseases, cancer biology, and neurodevelopmental disorders where SNX30 may play a pivotal role. By utilizing SNX30 Gene Knockout Cell Lines, scientists can dissect the molecular mechanisms underlying these conditions, explore novel therapeutic targets, and assess potential interventions with increased precision.
Compared to traditional wild-type models, the SNX30 knockout variants offer unique advantages, such as the ability to study the effects of gene loss in a controlled environment, facilitating the distinct observation of phenotype changes and cellular responses without the confounding influence of normal SNX30 function. Additionally, they enhance reproducibility in experimental setups, a critical factor for validating findings in drug discovery and developmental biology.
This product is of significant value to researchers, clinicians, and pharmaceutical developers alike, empowering them with the ability to conduct more targeted experiments that can lead to breakthroughs in our understanding of diseases associated with SNX30 dysfunction. With a commitment to innovative biological solutions, our company stands at the forefront of cutting-edge research, providing top-tier genetic models engineered for accuracy and reliability.
Please note that all services are for research use only. Not intended for any clinical use.
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