Gene: SNX21
Official Full Name: sorting nexin family member 21provided by HGNC
Gene Summary: This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members. The specific function of this protein has not been determined. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO23823 | SNX21 Knockout cell line (HeLa) | Human | SNX21 | 1:3~1:6 | Negative | Online Inquiry |
KO23824 | SNX21 Knockout cell line (HCT 116) | Human | SNX21 | 1:2~1:4 | Negative | Online Inquiry |
KO23825 | SNX21 Knockout cell line (HEK293) | Human | SNX21 | 1:3~1:6 | Negative | Online Inquiry |
KO23826 | SNX21 Knockout cell line (A549) | Human | SNX21 | 1:3~1:4 | Negative | Online Inquiry |
SNX21 Gene Knockout Cell Lines are precisely engineered cellular models designed to facilitate the investigation of the sorting nexin 21 (SNX21) gene’s function by eliminating its expression. This targeted genetic disruption allows researchers to explore the wide array of cellular processes influenced by SNX21, which is integral to membrane trafficking and endosomal sorting. Through the use of CRISPR/Cas9 technology, these knockout cell lines ensure a high degree of specificity and efficiency, enabling a clear understanding of the molecular pathways involving SNX21.
The key mechanisms by which SNX21 operates include its role in clathrin-mediated endocytosis and its involvement in the recycling pathways of various membrane proteins. By studying these knockout cell lines, researchers can delineate the impact of SNX21 on cellular functions, such as signal transduction, cellular communication, and the maintenance of cellular homeostasis. The knockout lines serve as a crucial tool in both fundamental and applied research settings, bridging our understanding of gene function in developmental biology, cancer research, and neurobiology.
One of the distinct advantages of SNX21 Gene Knockout Cell Lines is their reliability and reproducibility, offering a robust alternative to transient transfection methods or RNA interference approaches, which can often yield variable results. These cell lines provide a stable and constant experimental background, significantly improving the accuracy of experimental outcomes. Moreover, these models are compatible with high-throughput screening techniques, enhancing their utility in drug discovery and therapeutic development.
For researchers and clinicians focused on elucidating the biological role of SNX21, the availability of these knockout lines presents a valuable opportunity to investigate the gene's implications in disease states and potential therapeutic interventions. By leveraging these tools, professionals can contribute to the advancement of biomedical research and the development of novel therapeutic strategies.
With a commitment to excellence and innovation, our company specializes in the production of high-quality gene knockout cell lines, supported by a robust scientific understanding and state-of-the-art technology. We empower researchers with the tools they need to advance their investigations and push the boundaries of biological science.
Please note that all services are for research use only. Not intended for any clinical use.
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