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SNX18 Knockout Cell Lines

Gene: SNX18

Official Full Name: sorting nexin 18provided by HGNC

Gene Summary: This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members, but contains a SH3 domain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO30934 SNX18 Knockout cell line (HeLa) Human SNX18 1:3~1:6 Negative Online Inquiry
KO30935 SNX18 Knockout cell line (HCT 116) Human SNX18 1:2~1:4 Negative Online Inquiry
KO30936 SNX18 Knockout cell line (HEK293) Human SNX18 1:3~1:6 Negative Online Inquiry
KO30937 SNX18 Knockout cell line (A549) Human SNX18 1:3~1:4 Negative Online Inquiry

Background

SNX18 Gene Knockout Cell Lines are specialized cellular models in which the SNX18 gene has been functionally disrupted, enabling researchers to investigate the biological role of this specific gene in various physiological and pathological contexts. SNX18 encodes for sorting nexin 18, a protein implicated in membrane trafficking and endosomal dynamics, playing critical roles in cellular processes such as recycling and signal transduction. By utilizing these knockout cell lines, scientists can elucidate the implications of SNX18 loss on cellular behavior, shedding light on its involvement in diseases and potential therapeutic targets.

The key function of the SNX18 Gene Knockout Cell Lines lies in their ability to mimic the effects of genetic knockouts in vivo, providing a controlled environment for studying the downstream effects of SNX18 disruption. These models allow for the assessment of cellular pathways affected by SNX18, potentially influencing cancer progression, metabolic disorders, or neurodegeneration. Furthermore, the use of these cell lines can facilitate research on drug efficacy and mechanism of action in targeted therapies aimed at conditions where SNX18 is a contributing factor.

One of the scientific advantages of utilizing SNX18 Gene Knockout Cell Lines is their specificity and reproducibility compared to other methods, such as pharmacological inhibitors or general gene-silencing techniques, which may not provide consistent or targeted effects. Moreover, these knockout models offer a unique platform for high-throughput screening and functional genomics studies, enabling the identification of novel pathways and biomolecules involved in pathophysiological processes.

For researchers and clinicians, the availability of these cell lines is invaluable. They provide a robust tool for advancing the understanding of gene function and disease mechanisms while offering a potential gateway for developing innovative therapeutic strategies. The insights gained through studies utilizing SNX18 Gene Knockout Cell Lines may lead to breakthroughs in biomarker discovery or personalized medicine approaches in the treatment of complex diseases.

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Please note that all services are for research use only. Not intended for any clinical use.

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