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SNX16 Knockout Cell Lines

Gene: SNX16

Official Full Name: sorting nexin 16provided by HGNC

Gene Summary: This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. The protein encoded by this gene associates with late endosome membranes as is involved in tubule formation, cholesterol transport, and transport of tetraspanin CD81. The encoded protein also inhibits cell migration and tumorigenesis. [provided by RefSeq, Jan 2017]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO13858 SNX16 Knockout cell line (HeLa) Human SNX16 1:3~1:6 Negative Online Inquiry
KO13859 SNX16 Knockout cell line (HCT 116) Human SNX16 1:2~1:4 Negative Online Inquiry
KO13860 SNX16 Knockout cell line (HEK293) Human SNX16 1:3~1:6 Negative Online Inquiry
KO13861 SNX16 Knockout cell line (A549) Human SNX16 1:3~1:4 Negative Online Inquiry

Background

SNX16 Gene Knockout Cell Lines are innovative molecular tools designed to facilitate the study of the SNX16 gene, which encodes a member of the sorting nexin family known to play a pivotal role in endosomal trafficking and cellular communication. These cell lines are engineered through CRISPR/Cas9 technology, resulting in a targeted and precise disruption of the SNX16 gene, enabling researchers to explore its specific functions in various biological contexts.

The key mechanism underlying the usage of SNX16 Gene Knockout Cell Lines lies in their ability to mimic the loss-of-function scenarios. By creating a genomic knockout of SNX16, researchers can investigate the consequent phenotypic changes, cellular signaling pathways, and the gene's role in processes like endosomal sorting and receptor recycling. This experimental model is vital for understanding diseases associated with dysfunctional endosomal transport, such as neurodegenerative disorders and certain cancers.

In both research and clinical settings, SNX16 Gene Knockout Cell Lines serve as essential tools for drug discovery, pathway analysis, and the development of therapeutic strategies targeting endosomal dysfunction. The ability to analyze these lines in vitro supports translational efforts, helping bridge the gap from basic research to clinical applications.

Compared to alternative models that may require lengthy and complex genetic modification processes, SNX16 Gene Knockout Cell Lines offer a ready-to-use solution that can expedite research timelines significantly. Researchers benefit from the reduced background noise, increased specificity, and reproducibility of results, allowing for more targeted investigations of the SNX16 gene's role in cellular processes.

As a company committed to advancing molecular research, we equip scientists and clinicians with high-quality biological products that drive innovation. Our expertise in cell line development ensures that researchers have access to reliable, cutting-edge tools necessary for dissecting complex biological systems. Choose SNX16 Gene Knockout Cell Lines to elevate your research and unveil novel insights into cellular dynamics and pathology.

Please note that all services are for research use only. Not intended for any clinical use.

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