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SNX10 Knockout Cell Lines

Gene: SNX10

Official Full Name: sorting nexin 10provided by HGNC

Gene Summary: This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members. This gene may play a role in regulating endosome homeostasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO27003 SNX10 Knockout cell line (HCT 116) Human SNX10 1:2~1:4 Negative Online Inquiry
KO27004 SNX10 Knockout cell line (HEK293) Human SNX10 1:3~1:6 Negative Online Inquiry
KO27005 SNX10 Knockout cell line (A549) Human SNX10 1:3~1:4 Negative Online Inquiry

Background

SNX10 Gene Knockout Cell Lines are meticulously developed cellular models that facilitate the study of the SNX10 gene's role in various biological processes. By employing CRISPR-Cas9 technology, these cell lines provide a precise knockout of SNX10, allowing researchers to observe the resultant phenotypic changes and gain insights into the gene's function. The SNX10 protein is known to be involved in endosomal trafficking and has implications in cellular signaling pathways, making these knockout cell lines invaluable for understanding pathophysiological conditions associated with SNX10 dysregulation.

The key function of SNX10 Gene Knockout Cell Lines lies in their ability to provide a controlled environment in which the absence of SNX10 can be studied to elucidate its biological significance. Researchers can investigate various cellular processes such as protein sorting, membrane dynamics, and intracellular signaling by comparing knockout lines to wild-type counterparts. This allows for a deeper understanding of how mutations or deletions in the SNX10 gene could contribute to disease states, such as certain cancers or neurodegenerative disorders.

From a scientific perspective, the applications of SNX10 Gene Knockout Cell Lines extend to both fundamental research and clinical inquiries. They serve as powerful tools in drug discovery, where the delineation of molecular pathways influenced by SNX10 can lead to novel therapeutic targets. Additionally, these cell lines can assist in understanding genetic interactions and the development of gene therapies.

What sets SNX10 Gene Knockout Cell Lines apart from other models is their high specificity and reproducibility, which is often lacking in traditional genetic manipulation approaches. The CRISPR-Cas9-mediated knockout ensures that all phenotypic changes are attributable to the targeted gene absence, fostering robust and reliable experimental outcomes. This reliability is crucial for researchers committed to generating publishable data.

Investing in SNX10 Gene Knockout Cell Lines provides researchers and clinicians with a sophisticated platform for exploring the role of SNX10 in health and disease, translating findings into tangible advancements in science and medicine. With our years of expertise in gene editing and cellular model systems, we ensure that our products are of the highest quality, catering to the evolving needs of the scientific community.

Please note that all services are for research use only. Not intended for any clinical use.

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