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SNAP91 Knockout Cell Lines

Gene: SNAP91

Official Full Name: synaptosome associated protein 91provided by HGNC

Gene Summary: Predicted to enable several functions, including clathrin adaptor activity; clathrin heavy chain binding activity; and phosphatidylinositol binding activity. Acts upstream of or within regulation of clathrin-dependent endocytosis. Predicted to be located in cytosol; postsynaptic density; and synaptic membrane. Predicted to be active in several cellular components, including Schaffer collateral - CA1 synapse; cytoplasmic vesicle; and parallel fiber to Purkinje cell synapse. Predicted to be extrinsic component of presynaptic endocytic zone membrane. Biomarker of Alzheimer's disease. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO32563 SNAP91 Knockout cell line (HEK293) Human SNAP91 1:3~1:6 Negative Online Inquiry

Background

SNAP91 Gene Knockout Cell Lines are meticulously engineered cellular models designed to facilitate the study of the SNAP91 gene's functions and regulatory mechanisms. These cell lines are generated through advanced gene-editing technologies, such as CRISPR/Cas9, resulting in specific deletion of the SNAP91 gene, thereby enabling researchers to observe the resultant phenotypic changes and associated molecular pathways.

These knockout cell lines empower scientific inquiry by providing a platform for investigating the role of SNAP91 in various biological processes, including cell signaling, receptor-mediated endocytosis, and synaptic transmission. By reducing or eliminating SNAP91 expression, researchers can elucidate the gene's contributions to neurodevelopmental disorders or metabolic pathways, effectively bridging basic research with potential therapeutic applications. The ability to directly manipulate the SNAP91 gene in relevant cellular backgrounds enhances the accuracy of experimental findings, fostering a deeper understanding of gene function in diverse contexts.

Compared to standard wild-type cell lines, SNAP91 knockout models boast unique advantages, such as enhanced specificity in elucidating gene function, reduced background noise from other pathways, and the potential for high-throughput screening applications in drug discovery. Furthermore, these cell lines are invaluable for exploring gene-gene interactions and characterizing compensatory mechanisms that can arise in knockout scenarios.

The SNAP91 Gene Knockout Cell Lines are ideal tools for researchers and clinicians aiming to advance our comprehension of gene function and its implications in health and disease. By supporting a nuanced understanding of molecular interactions, these models lay the groundwork for developing novel therapeutic strategies.

Our company specializes in providing high-quality biological products that enable cutting-edge research and clinical innovation. With a commitment to scientific excellence, we ensure that our knockout cell lines meet rigorous quality standards, allowing researchers to focus on discovery without compromise.

Please note that all services are for research use only. Not intended for any clinical use.

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