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SNAP47 Knockout Cell Lines

Gene: SNAP47

Official Full Name: synaptosome associated protein 47provided by HGNC

Gene Summary: Predicted to enable SNAP receptor activity and syntaxin binding activity. Predicted to be involved in synaptic vesicle fusion to presynaptic active zone membrane and synaptic vesicle priming. Predicted to act upstream of or within long-term synaptic potentiation. Located in BLOC-1 complex. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO30488 SNAP47 Knockout cell line (HeLa) Human SNAP47 1:3~1:6 Negative Online Inquiry
KO30489 SNAP47 Knockout cell line (HCT 116) Human SNAP47 1:2~1:4 Negative Online Inquiry
KO30490 SNAP47 Knockout cell line (HEK293) Human SNAP47 1:3~1:6 Negative Online Inquiry
KO30491 SNAP47 Knockout cell line (A549) Human SNAP47 1:3~1:4 Negative Online Inquiry

Background

SNAP47 Gene Knockout Cell Lines are genetically modified cellular models created to lack the expression of the SNAP47 (Synaptosomal-Associated Protein 47) gene, which is vital for the regulation of synaptic function and vesicle trafficking in neuronal cells. By targeting and disrupting the SNAP47 gene, these cell lines allow researchers to study the specific roles and functional implications of SNAP47 in various biological processes, including neurotransmitter release, synaptic integrity, and neurological disorders.

The mechanism of action involves the precise editing of the SNAP47 gene using advanced techniques such as CRISPR-Cas9 technology, leading to a stable and reproducible loss of function. This knockout model enables scientists to analyze the consequences of SNAP47 deficiency at cellular and molecular levels, providing insights into synaptic transmission dysfunctions and their associations with diseases such as Alzheimer’s and schizophrenia.

The scientific importance of SNAP47 Gene Knockout Cell Lines is underscored by their utility in both fundamental research and clinical applications. These cell lines facilitate the exploration of disease mechanisms, making them invaluable tools for pharmacological studies, biomarker identification, and the development of novel therapeutic strategies. Their reproducible outcomes and relevance to human biology enhance their utility in translational research.

A significant advantage of our SNAP47 Gene Knockout Cell Lines is the rigorous validation process they undergo, ensuring high specificity and efficiency in gene editing. Unlike other models that may suffer from incomplete knockout or off-target effects, our lines guarantee precise alterations that foster reliable data interpretation. Furthermore, these cell lines are convenient to use and adaptable for various experimental designs, making them a preferred choice over traditional wild-type cells or other knockout models.

In summary, SNAP47 Gene Knockout Cell Lines are a cutting-edge addition to the biologist's toolkit, allowing for detailed exploration into the complexities of synaptic mechanisms and neurobiology. Their reliability and ease of use feature our commitment to providing researchers with innovative products designed to advance science. At [Your Company Name], we pride ourselves on our expertise in cell line development, continuously striving to meet the evolving needs of the scientific community.

Please note that all services are for research use only. Not intended for any clinical use.

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