Gene: SMTNL2
Official Full Name: smoothelin like 2provided by HGNC
Gene Summary: Predicted to be involved in actin cytoskeleton organization. Predicted to be part of filamentous actin. Predicted to be active in microtubule organizing center. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO13887 | SMTNL2 Knockout cell line (HCT 116) | Human | SMTNL2 | 1:2~1:4 | Negative | Online Inquiry |
KO13888 | SMTNL2 Knockout cell line (HEK293) | Human | SMTNL2 | 1:3~1:6 | Negative | Online Inquiry |
SMTNL2 Gene Knockout Cell Lines are genetically engineered cell lines in which the SMTNL2 gene has been selectively disrupted or inactivated. This innovative product allows researchers to study the biological role of the SMTNL2 protein, which is involved in various cellular processes, including cell signaling, cytoskeletal organization, and cellular response to stress. By providing a model system that lacks the functional SMTNL2 protein, researchers can elucidate its contributions to physiological and pathological conditions, thereby advancing their understanding of numerous diseases, particularly those related to cancer and cardiovascular health.
The primary mechanism by which SMTNL2 Gene Knockout Cell Lines function is through the absence of the SMTNL2 protein, allowing for the investigation of downstream signaling pathways and cellular behaviors that are otherwise confounded by the presence of functional protein. These knockout models enable the exploration of compensatory mechanisms employed by cells, helping scientists identify alternative pathways or genetic interactions that may be activated in the absence of SMTNL2.
In terms of scientific importance, SMTNL2 Gene Knockout Cell Lines hold significant application potential in both basic and translational research. Clinically, understanding the role of SMTNL2 can help in identifying novel biomarkers for disease or new therapeutic targets in surgeries and drug development. By providing a precise tool to dissect the functional implications of SMTNL2 loss, this product promotes enhanced insights into the molecular underpinnings of various conditions and aids in therapeutic strategy development.
Compared to alternatives, such as traditional overexpression models or unspecific siRNA knockdown, SMTNL2 Gene Knockout Cell Lines offer a more robust and definitive analysis of gene function. With a complete removal of the gene, researchers can obtain clearer results without the risk of compensatory effects that may arise from other methods.
The value of SMTNL2 Gene Knockout Cell Lines cannot be understated for researchers and clinicians alike. They represent a cutting-edge resource for advancing knowledge and augmenting research capabilities in cellular and molecular biology. By facilitating deeper insights into cellular mechanisms, this product empowers scientists to drive forward discoveries with potential implications for improving human health.
Our company specializes in providing high-quality genetic tools and biologics, underpinned by years of expertise in molecular biology. We are committed to equipping researchers and clinicians with innovative resources that enhance experimental outcomes and foster breakthroughs in biological science.
Please note that all services are for research use only. Not intended for any clinical use.
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