Gene: SMIM12
Official Full Name: small integral membrane protein 12provided by HGNC
Gene Summary: Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO30841 | SMIM12 Knockout cell line (HeLa) | Human | SMIM12 | 1:3~1:6 | Negative | Online Inquiry |
KO30842 | SMIM12 Knockout cell line (HCT 116) | Human | SMIM12 | 1:2~1:4 | Negative | Online Inquiry |
KO30843 | SMIM12 Knockout cell line (HEK293) | Human | SMIM12 | 1:3~1:6 | Negative | Online Inquiry |
KO30844 | SMIM12 Knockout cell line (A549) | Human | SMIM12 | 1:3~1:4 | Negative | Online Inquiry |
SMIM12 Gene Knockout Cell Lines represent a revolutionary advancement in molecular biology, specifically designed for the targeted gene knockout of SMIM12 (Small Integral Membrane Protein 12). These cell lines facilitate the precise investigation of the gene's function by eliminating its expression, which allows researchers to study the resulting phenotypic changes in various biological contexts. This targeted approach aids in elucidating the role of SMIM12 in cellular processes and disease mechanisms, providing pivotal insights for both fundamental and applied research.
The primary function of the SMIM12 Gene Knockout Cell Lines is to provide a controlled environment to assess the impact of SMIM12 deletion on cell functionality, signaling pathways, and gene expression profiles. By utilizing CRISPR-Cas9 technology for the knockout procedure, these cell lines ensure high efficiency and specificity in gene editing, minimizing off-target effects commonly associated with traditional methods. This precision enables researchers to dissect the biological roles of SMIM12 in cellular responses, metabolic pathways, and potential contributions to disease states.
The scientific importance of these knockout cell lines extends into various research arenas, including cancer biology, immunology, and drug discovery. They serve as vital tools in elucidating the underlying mechanisms of diseases influenced by SMIM12, offering potential avenues for therapeutic intervention. Furthermore, such knockout models are invaluable in pharmaceutical screening processes, streamlining the identification of compounds that modulate gene function or mimic its activity.
Compared to alternative gene editing options, the SMIM12 Gene Knockout Cell Lines stand out due to their robust validation, extensive characterization, and compatibility with a range of assays, including cellular signaling studies and high-throughput screening. This specificity not only enhances the reliability of experimental outcomes but also mitigates variability, ensuring reproducibility in research findings.
For researchers and clinicians seeking reliable models to unravel complex biological systems, the SMIM12 Gene Knockout Cell Lines provide unparalleled value by accelerating scientific discovery and enhancing translational research outcomes. With a commitment to quality and innovation, our company leverages extensive expertise in cellular biology and genetic engineering, ensuring these products meet the highest standards for research excellence.
Please note that all services are for research use only. Not intended for any clinical use.
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