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SMIM1 Knockout Cell Lines

Gene: SMIM1

Official Full Name: small integral membrane protein 1 (Vel blood group)provided by HGNC

Gene Summary: This gene encodes a small, conserved protein that participates in red blood cell formation. The encoded protein is localized to the cell membrane and is the antigen for the Vel blood group. Alternative splicing results in different transcript variants that encode the same protein. [provided by RefSeq, Dec 2013]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO13935 SMIM1 Knockout cell line (HeLa) Human SMIM1 1:3~1:6 Negative Online Inquiry
KO13936 SMIM1 Knockout cell line (HCT 116) Human SMIM1 1:2~1:4 Negative Online Inquiry
KO13937 SMIM1 Knockout cell line (HEK293) Human SMIM1 1:3~1:6 Negative Online Inquiry

Background

SMIM1 Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to silence the expression of the SMIM1 gene, which encodes a small integral membrane protein involved in various cellular functions. These knockout cell lines can be a powerful tool for researchers seeking to understand the biological role of SMIM1 and its implications in cellular processes such as cell proliferation, apoptosis, and signal transduction. By utilizing CRISPR/Cas9 technology or other genome editing techniques, the SMIM1 gene has been systematically disrupted, allowing for detailed mechanistic studies of gene function and protein interactions.

The primary function of SMIM1 Gene Knockout Cell Lines lies in their ability to facilitate the study of SMIM1-related pathways. By observing the cellular alterations that occur following gene disruption, researchers can delineate the effects of SMIM1 on diverse biological responses and potential dysregulations in diseases such as cancer or metabolic disorders. This provides valuable insights that can drive forward therapeutic strategies and inform clinical practices.

In comparison to traditional methods of gene knockdown, such as RNA interference, knockout cell lines offer a more stable and permanent alteration of gene expression, enabling longitudinal studies that track phenotypic outcomes over time. Moreover, because these cell lines are fully characterized and validated, they provide a reliable platform for reproducible experimental results.

For researchers and clinicians alike, SMIM1 Gene Knockout Cell Lines are invaluable in elucidating the roles of specific genes in disease mechanisms, which can facilitate the development of gene-targeted therapies. The ability to conduct high-throughput screening or perform co-culture experiments with these knockout lines can significantly enhance experimental design, ultimately leading to groundbreaking discoveries.

With extensive experience in the development of cellular models and a commitment to providing cutting-edge biological products, our company stands as a leader in the field, ready to support researchers in advancing their scientific endeavors through high-quality, innovative tools like SMIM1 Gene Knockout Cell Lines.

Please note that all services are for research use only. Not intended for any clinical use.

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