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SLF2 Knockout Cell Lines

Gene: SLF2

Official Full Name: SMC5-SMC6 complex localization factor 2provided by HGNC

Gene Summary: Enables ubiquitin protein ligase binding activity. Involved in several processes, including positive regulation of cellular component organization; positive regulation of double-strand break repair; and protein localization to site of double-strand break. Located in PML body; chromatin; and site of double-strand break. Implicated in mosaic variegated aneuploidy syndrome. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO13977 SLF2 Knockout cell line (HeLa) Human SLF2 1:3~1:6 Negative Online Inquiry
KO13978 SLF2 Knockout cell line (HCT 116) Human SLF2 1:2~1:4 Negative Online Inquiry
KO13979 SLF2 Knockout cell line (HEK293) Human SLF2 1:3~1:6 Negative Online Inquiry
KO13980 SLF2 Knockout cell line (A549) Human SLF2 1:3~1:4 Negative Online Inquiry

Background

SLF2 Gene Knockout Cell Lines are a cutting-edge biological tool specifically designed for the study of gene function and regulation within cellular contexts. These cell lines contain targeted deletions of the SLF2 gene, enabling scientists to investigate its biological roles, interactions with other cellular pathways, and implications in various disease models. The genetic modification employed in creating these knockout lines utilizes CRISPR-Cas9 technology, which allows for precise genome editing, ensuring high efficiency and specificity in gene ablation.

The primary function of SLF2 Gene Knockout Cell Lines is to facilitate in-depth research into the implications of SLF2 in cellular processes such as apoptosis, cell proliferation, and stress responses. By observing the phenotypic and molecular changes arising from the absence of SLF2, researchers can unravel the mechanisms of action it exerts within the cell. This includes examining the pathways that SLF2 is known to modulate, aiding in the identification of potential therapeutic targets for various diseases, including cancer and metabolic disorders.

The scientific importance of these cell lines extends to versatile applications in both research and clinical settings. They provide a platform for drug discovery and functional genomics, contributing significantly to the field of target identification and validation. Additionally, they enable researchers to create more accurate models of disease by eliminating confounding genetic variables, promoting the development of more effective and personalized treatment strategies.

One of the standout advantages of SLF2 Gene Knockout Cell Lines is their robustness and reproducibility. Unlike traditional methods of gene knockdown, which may yield variable results due to incomplete silencing, these knockout cell lines provide a stable, genetically modified system that ensures consistency across experiments. Furthermore, their compatibility with various assays allows for seamless integration into established research workflows.

For researchers and clinicians, the value of SLF2 Gene Knockout Cell Lines lies in their ability to simplify complex experimental designs and accelerate discoveries in genomics and molecular biology. As such, our company is committed to delivering high-quality biological products supported by rigorous scientific validation, enhancing research capabilities and fostering innovation in life sciences. With our expertise, we ensure that your investigations into gene function and therapy development are both efficient and impactful.

Please note that all services are for research use only. Not intended for any clinical use.

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