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SLC5A6 Knockout Cell Lines

Gene: SLC5A6

Official Full Name: solute carrier family 5 member 6provided by HGNC

Gene Summary: Enables biotin transmembrane transporter activity; iodide transmembrane transporter activity; and pantothenate transmembrane transporter activity. Involved in iodide transmembrane transport; transport across blood-brain barrier; and vitamin transmembrane transport. Located in apical plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO33763 SLC5A6 Knockout cell line (HeLa) Human SLC5A6 1:3~1:6 Negative Online Inquiry
KO33764 SLC5A6 Knockout cell line (HCT 116) Human SLC5A6 1:2~1:4 Negative Online Inquiry
KO33765 SLC5A6 Knockout cell line (HEK293) Human SLC5A6 1:3~1:6 Negative Online Inquiry
KO33766 SLC5A6 Knockout cell line (A549) Human SLC5A6 1:3~1:4 Negative Online Inquiry

Background

SLC5A6 Gene Knockout Cell Lines are specialized cellular models designed to study the functional roles of the SLC5A6 gene, which encodes a sodium-dependent glucose transporter integral to cellular glucose homeostasis and nutrient absorption. By utilizing gene editing technologies such as CRISPR/Cas9, these cell lines allow researchers to precisely disrupt the SLC5A6 gene, creating a loss-of-function model that facilitates the investigation of its biological significance.

The primary function of SLC5A6 is to facilitate the active transport of glucose into cells, thereby influencing metabolic processes. Knockout of this gene can elucidate its impact on glucose metabolism, cellular signaling pathways, and overall energy balance. Such insights are paramount for understanding various metabolic disorders, including diabetes and obesity, where glucose transport plays a critical role.

Scientifically, SLC5A6 knockout cell lines are invaluable in both research and clinical settings. They enable the development of new therapies targeting glucose transport mechanisms and foster drug discovery efforts aimed at metabolic diseases. By providing a platform to study the gene's role in disease states, these cell lines can drive innovation in therapeutic strategies.

Compared to alternative models, SLC5A6 knockout cell lines offer increased specificity and reliability in experimental outcomes. They present a controlled environment that closely mimics physiological conditions, allowing for accurate assessment of gene function and drug responses. This specificity markedly reduces the variability often encountered in traditional models, making these cell lines a superior choice for researchers.

For scientists and clinicians seeking to unravel the complexities of glucose metabolism and its implications in health and disease, SLC5A6 Gene Knockout Cell Lines provide a robust research tool. They are meticulously developed in a lab with a strong commitment to quality and innovation. Our company prides itself on delivering state-of-the-art biological products that empower researchers to advance their studies and clinical applications with confidence.

Please note that all services are for research use only. Not intended for any clinical use.

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