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SLC44A5 Knockout Cell Lines

Gene: SLC44A5

Official Full Name: solute carrier family 44 member 5provided by HGNC

Gene Summary: Enables choline transmembrane transporter activity. Involved in choline transport. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO34805 SLC44A5 Knockout cell line (HeLa) Human SLC44A5 1:3~1:6 Negative Online Inquiry
KO34806 SLC44A5 Knockout cell line (HCT 116) Human SLC44A5 1:2~1:4 Negative Online Inquiry
KO34807 SLC44A5 Knockout cell line (HEK293) Human SLC44A5 1:3~1:6 Negative Online Inquiry

Background

SLC44A5 Gene Knockout Cell Lines are specialized cell lines engineered to lack the expression of the SLC44A5 gene, which encodes for a protein implicated in various biological processes, including cell adhesion, response to environmental stimuli, and potential roles in inflammatory responses. By utilizing CRISPR-Cas9 gene editing technology, these knockout cell lines create a robust model to investigate the functions of SLC44A5 in cellular mechanisms and disease states.

The primary function of SLC44A5 knockout cell lines lies in their ability to elucidate the downstream effects of SLC44A5 absence, providing critical insights into the gene's role in cellular processes. Researchers can study changes in cell morphology, adhesion properties, and signaling pathways, facilitating the understanding of complex cellular interactions, especially in contexts such as immune response and cancer biology.

The scientific importance of these knockout cell lines extends to diverse applications in both research and clinical settings. They serve as invaluable tools for studying disease mechanisms, drug development, and potential therapeutic interventions, especially focusing on inflammatory diseases and cancer progression. Furthermore, they are ideal for high-throughput screening and validation of therapeutic targets.

What sets our SLC44A5 Gene Knockout Cell Lines apart from existing alternatives is the precision and efficiency of the knockout achieved, alongside comprehensive characterization of the resultant cell lines. Unlike traditional knockout models that may exhibit pleiotropy or incomplete knockout, our engineered lines maintain high specificity and reliability, ensuring that experimental outcomes are robust and reproducible.

For researchers and clinicians, the value of these cell lines cannot be overstated. With their application enhancing biological understanding and facilitating translational research, they provide a significant advantage in developing targeted therapies. Our commitment to high-quality biological products is backed by a team of experts who ensure that each cell line is rigorously validated and characterized, offering unparalleled support in your research endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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