Gene: SLC44A2
Official Full Name: solute carrier family 44 member 2 (CTL2 blood group)provided by HGNC
Gene Summary: Enables choline transmembrane transporter activity and ethanolamine transmembrane transporter activity. Involved in choline transport; ethanolamine transport; and transmembrane transport. Located in mitochondrial outer membrane and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO05718 | SLC44A2 Knockout cell line (HeLa) | Human | SLC44A2 | 1:3~1:6 | Negative | Online Inquiry |
KO05719 | SLC44A2 Knockout cell line (HCT 116) | Human | SLC44A2 | 1:2~1:4 | Negative | Online Inquiry |
KO05720 | SLC44A2 Knockout cell line (HEK293) | Human | SLC44A2 | 1:3~1:6 | Negative | Online Inquiry |
KO05721 | SLC44A2 Knockout cell line (A549) | Human | SLC44A2 | 1:3~1:4 | Negative | Online Inquiry |
SLC44A2 Gene Knockout Cell Lines are a specialized biological tool designed for the investigation of SLC44A2, a gene implicated in various physiological and pathological processes, particularly in cell metabolism and disease states. These cell lines are engineered to have a complete disruption of the SLC44A2 gene, enabling researchers to study the resulting phenotypic changes and cellular functions devoid of this specific genetic element.
The primary function of the SLC44A2 Gene Knockout Cell Lines is to elucidate the role of the SLC44A2 gene in cellular transport, signaling pathways, and metabolic processes. By examining how the absence of SLC44A2 affects cellular behavior, researchers can uncover insights into its contributions to disease mechanisms, such as neurological disorders and metabolic syndromes. The mechanism of action involves the genetic deletion of the gene using CRISPR-Cas9 technology, which offers precise and efficient genomic editing, ensuring the validity of experimental outcomes.
The scientific importance of these cell lines extends to both research and clinical applications. In research settings, these knockout models can be crucial for drug discovery, toxicology assessments, and biomarker identification. Clinically, understanding SLC44A2's role could lead to novel therapeutic targets and strategies for diseases where SLC44A2 is a key player.
Compared to traditional cell lines, the SLC44A2 Gene Knockout Cell Lines provide unique advantages such as specificity and reproducibility in experimental results. Their targeted nature eliminates confounding variables associated with non-specific gene silencing techniques, rendering them invaluable for researchers who require clarity in their experimental models.
This product is a vital asset for researchers and clinicians aiming to deepen their understanding of SLC44A2's function and its implications in health and disease. Utilizing these knockout cell lines enhances the ability to develop innovative approaches to treatment and precision medicine.
With a strong commitment to advancing biological research, our company specializes in providing high-quality genetic models, including SLC44A2 Gene Knockout Cell Lines, enabling the scientific community to push the boundaries of knowledge and discovery.
Please note that all services are for research use only. Not intended for any clinical use.
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