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SLC43A3 Knockout Cell Lines

Gene: SLC43A3

Official Full Name: solute carrier family 43 member 3provided by HGNC

Gene Summary: Enables adenine transmembrane transporter activity; guanine transmembrane transporter activity; and xenobiotic transmembrane transporter activity. Involved in hypoxanthine transport. Located in basolateral plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO02316 SLC43A3 Knockout cell line (HeLa) Human SLC43A3 1:3~1:6 Negative Online Inquiry
KO02317 SLC43A3 Knockout cell line (HCT 116) Human SLC43A3 1:2~1:4 Negative Online Inquiry

Background

SLC43A3 Gene Knockout Cell Lines are genetically modified cellular models designed to lack the expression of the SLC43A3 gene, which plays a critical role in the transport of large neutral amino acids across cell membranes. This bioresearch tool provides invaluable insights into the physiological and pathological roles of SLC43A3, specifically its involvement in amino acid homeostasis, metabolic regulation, and potential implications in diseases like cancer and metabolic disorders.

The primary mechanism underlying the functionality of SLC43A3 Gene Knockout Cell Lines lies in their altered transport dynamics, allowing researchers to study the effects of the absence of SLC43A3 on cellular growth, differentiation, and signaling pathways. By providing a platform to evaluate how the loss of this gene affects amino acid transport and subsequent metabolic outcomes, these cell lines can illuminate mechanisms that could inform therapeutic strategies.

Scientifically, SLC43A3 Gene Knockout Cell Lines serve as crucial models in pharmacological studies and experimental therapies, bridging gaps in our understanding of amino acid transport in human health and disease. Their applications extend to drug discovery, where understanding the role of amino acid transport can lead to more targeted and effective treatments for metabolic conditions.

Unique advantages over traditional models include the precise knockout of the target gene, which enhances the specificity of experimental results and reduces confounding factors often present in wild-type systems. Additionally, these cell lines are easy to use and compatible with a variety of assay systems, making them versatile tools for both basic and applied research.

Researchers and clinicians will find immense value in employing SLC43A3 Gene Knockout Cell Lines as they investigate novel therapeutic avenues or mechanistic studies. The insights garnered from these models not only advance scientific understanding but also have the potential to drive innovation in treatment approaches.

With a strong foundation in cutting-edge genetics and a commitment to quality, our company specializes in providing high-fidelity biological research tools, including the SLC43A3 Gene Knockout Cell Lines, to empower the scientific community and accelerate discovery in the biomedical field.

Please note that all services are for research use only. Not intended for any clinical use.

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