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SLC43A1 Knockout Cell Lines

Gene: SLC43A1

Official Full Name: solute carrier family 43 member 1provided by HGNC

Gene Summary: SLC43A1 belongs to the system L family of plasma membrane carrier proteins that transports large neutral amino acids (Babu et al., 2003 [PubMed 12930836]).[supplied by OMIM, Mar 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO34119 SLC43A1 Knockout cell line (HCT 116) Human SLC43A1 1:2~1:4 Negative Online Inquiry
KO34120 SLC43A1 Knockout cell line (HEK293) Human SLC43A1 1:3~1:6 Negative Online Inquiry
KO34121 SLC43A1 Knockout cell line (A549) Human SLC43A1 1:3~1:4 Negative Online Inquiry

Background

SLC43A1 Gene Knockout Cell Lines are specifically engineered cellular models that have undergone targeted gene disruption of the SLC43A1 gene, which encodes for a solute carrier protein involved in the transport of diverse substrates across cell membranes. The primary function of these cell lines is to facilitate the study of SLC43A1’s role in cellular processes such as amino acid transport, metabolic regulation, and its implications in disease states like cancer and metabolic disorders. By utilizing CRISPR-Cas9 or other gene-editing technologies, these cell lines provide a controlled environment to investigate gene function, signaling pathways, and potential gene interactions.

The scientific importance of SLC43A1 knockout cell lines is particularly evident in research and clinical settings, where understanding the genetic underpinnings of diseases can drive therapeutic development. These models offer unique insights into the cellular mechanisms at play during amino acid transport deficiencies or malfunctions, providing valuable data that can inform drug discovery and disease prevention strategies.

Compared to traditional cell lines that may exhibit normal gene function, SLC43A1 knockout lines represent a significant advancement by allowing researchers to observe the effects of the absence of this gene directly. This specificity enhances the reliability and reproducibility of experimental results, making these cell lines indispensable tools in both basic and applied biological research.

For researchers and clinicians, the use of SLC43A1 Gene Knockout Cell Lines equates to enhanced capabilities for elucidating disease mechanisms and screening for potential pharmacological agents. The precision of these knockout models thus accelerates the pathway from laboratory discovery to clinical application, ensuring that findings can rapidly transition into meaningful therapeutic avenues.

Our company specializes in providing high-quality, reliable genetic knockout cell lines, backed by a strong commitment to advancing biomedical research. With our expertise, researchers gain access to innovative tools that are crucial for pioneering discoveries in the molecular biology landscape.

Please note that all services are for research use only. Not intended for any clinical use.

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