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SLC30A6 Knockout Cell Lines

Gene: SLC30A6

Official Full Name: solute carrier family 30 member 6provided by HGNC

Gene Summary: This gene encodes a member of a family of proteins that function as zinc transporters. This protein can regulate subcellular levels of zinc in the Golgi and vesicles. Expression of this gene is altered in the Alzheimer's disease brain plaques. [provided by RefSeq, Aug 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO14037 SLC30A6 Knockout cell line (HeLa) Human SLC30A6 1:3~1:6 Negative Online Inquiry
KO14038 SLC30A6 Knockout cell line (HCT 116) Human SLC30A6 1:2~1:4 Negative Online Inquiry
KO14039 SLC30A6 Knockout cell line (HEK293) Human SLC30A6 1:3~1:6 Negative Online Inquiry
KO14040 SLC30A6 Knockout cell line (A549) Human SLC30A6 1:3~1:4 Negative Online Inquiry

Background

SLC30A6 Gene Knockout Cell Lines are specialized cell lines engineered to have a targeted disruption of the SLC30A6 gene, which encodes a zinc transporter vital for cellular zinc homeostasis. By utilizing CRISPR/Cas9 technology, these cell lines allow for precise genetic modifications, thereby enabling researchers to investigate the specific roles and pathways associated with SLC30A6 in various biological processes. The knockout of this gene provides crucial insights into its contribution to zinc metabolism, cellular signaling, and potential implications in diseases characterized by dysregulated zinc homeostasis.

The key functions of SLC30A6 involve maintaining intracellular zinc levels, which are critical for protein synthesis, enzyme function, and nucleic acid stabilization. The disruption of SLC30A6 alters cellular responses to zinc fluctuations, making it a valuable tool for understanding the molecular mechanisms governing zinc-dependent diseases and conditions such as neurodegeneration, cancer, and metabolic syndromes. Researchers can utilize these cell lines to model disease states, screen potential therapeutics, and elucidate the physiological impact of zinc deficiency or overload.

The scientific importance of SLC30A6 Gene Knockout Cell Lines lies in their ability to provide insights into the physiological roles of zinc transporters in health and disease. This product facilitates in-depth exploration of gene function with a level of specificity and control that traditional methodologies may not achieve. Compared to alternative approaches, such as pharmacological inhibition or non-specific knockdown techniques, these knockout cell lines offer a more reliable and reproducible platform for mechanistic studies, enhancing the reliability of experimental outcomes.

For researchers and clinicians, the value of SLC30A6 Gene Knockout Cell Lines is multifaceted. They not only advance basic understanding of zinc's role in cell biology but also set the stage for discovering novel therapeutic targets. Understanding how the absence of SLC30A6 alters cellular behavior can open avenues for innovative treatments in diseases exacerbated by zinc imbalances.

Our company specializes in providing high-quality genetic tools tailored for cutting-edge research. With a strong emphasis on scientific integrity and innovative methodologies, we are committed to supporting your research endeavors with products like the SLC30A6 Gene Knockout Cell Lines, empowering you to unlock new knowledge in the realm of cellular biology and therapeutic development.

Please note that all services are for research use only. Not intended for any clinical use.

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