Gene: SLC2A5
Official Full Name: solute carrier family 2 member 5provided by HGNC
Gene Summary: The protein encoded by this gene is a fructose transporter responsible for fructose uptake by the small intestine. The encoded protein also is necessary for the increase in blood pressure due to high dietary fructose consumption. [provided by RefSeq, Jun 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO06576 | SLC2A5 Knockout cell line (HeLa) | Human | SLC2A5 | 1:3~1:6 | Negative | Online Inquiry |
SLC2A5 Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to investigate the functional role of the SLC2A5 gene, which encodes the fructose transporter responsible for cellular fructose uptake. By utilizing CRISPR-Cas9 technology, these cell lines exhibit precise deletions of the SLC2A5 gene, enabling researchers to study its biological functions and associated metabolic pathways in a controlled environment.
The key mechanism underlying these knockout cell lines is the targeted mutagenesis facilitated by CRISPR components, allowing for the reliable and reproducible disruption of the SLC2A5 gene. This process results in the absence of the SLC2A5 protein, offering a remarkable opportunity to examine the effects of fructose transport deficiency and its impact on cellular metabolism, signaling pathways, and related physiological processes.
The scientific importance of SLC2A5 Gene Knockout Cell Lines lies in their application across various research fields, including metabolic disorders, oncology, and nutrition. These cell lines are instrumental for studying conditions such as insulin resistance, obesity, and cancer cell proliferation, providing insights into the therapeutic potential of modulating fructose metabolism. In clinical settings, they can contribute to the development of targeted therapies aimed at managing fructose-related disorders.
What sets SLC2A5 Gene Knockout Cell Lines apart from conventional models is their specificity and reliability. Unlike transient knockdown approaches that often yield inconsistent results, these stable knockouts provide a robust tool for long-term studies. Researchers benefit from easier data interpretation and reproducibility, making the experimental design more effective.
For researchers and clinicians focused on metabolic research or therapeutic development, SLC2A5 Gene Knockout Cell Lines represent a valuable asset, facilitating groundbreaking discoveries and knowledge advancement in the field of metabolic health. Our company, committed to cutting-edge genetic research tools, takes pride in offering meticulously developed cell lines that streamline the investigative process, empowering the scientific community to accelerate their findings with confidence and precision.
Please note that all services are for research use only. Not intended for any clinical use.
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