Gene: SLC2A12
Official Full Name: solute carrier family 2 member 12provided by HGNC
Gene Summary: SLC2A12 belongs to a family of transporters that catalyze the uptake of sugars through facilitated diffusion (Rogers et al., 2002). This family of transporters show conservation of 12 transmembrane helices as well as functionally significant amino acid residues (Joost and Thorens, 2001 [PubMed 11780753]).[supplied by OMIM, Mar 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO21469 | SLC2A12 Knockout cell line (HeLa) | Human | SLC2A12 | 1:3~1:6 | Negative | Online Inquiry |
KO21470 | SLC2A12 Knockout cell line (HEK293) | Human | SLC2A12 | 1:3~1:6 | Negative | Online Inquiry |
SLC2A12 Gene Knockout Cell Lines are specially engineered cellular models designed to facilitate the study of the SLC2A12 gene, which encodes a glucose transporter protein implicated in glucose homeostasis and insulin signaling. By employing CRISPR-Cas9 gene-editing technology, these knockout cell lines exhibit a complete absence of SLC2A12 expression, allowing researchers to investigate the gene's biological functions and its role in metabolic disorders, such as diabetes and obesity.
The primary function of these cell lines is to provide an in vitro system for studying the physiological consequences of SLC2A12 gene disruption. Researchers can observe alterations in glucose uptake, alterations in downstream signaling pathways, and modifications in cellular metabolism. The knockout models serve as critical tools for elucidating the mechanisms involved in diseases associated with glucose metabolism, offering insights that may lead to the development of new therapeutic strategies.
In scientific research and clinical settings, SLC2A12 Gene Knockout Cell Lines hold immense importance as they provide a platform for drug screening and the evaluation of therapeutic compounds aimed at modulating SLC2A12 activity. Their use extends to metabolic research, cardiovascular studies, and investigations into the intricate processes of cellular energy regulation.
What sets our SLC2A12 Gene Knockout Cell Lines apart from alternatives is their high specificity and reliable reproducibility. Our product has undergone thorough validation, ensuring that researchers obtain consistent results. Furthermore, these cell lines can be cultured under standard laboratory conditions, making them a straightforward addition to existing workflows.
For researchers and clinicians dedicated to understanding metabolic diseases and seeking innovative treatments, the SLC2A12 Gene Knockout Cell Lines provide invaluable resources that could accelerate breakthroughs in the field. Our company, recognized for its commitment to quality and innovation in biological products, offers dependable resources that support the cutting-edge research of today and the medical advancements of tomorrow.
Please note that all services are for research use only. Not intended for any clinical use.
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