Gene: SLC25A45
Official Full Name: solute carrier family 25 member 45provided by HGNC
Gene Summary: Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in mitochondrial inner membrane. Predicted to be active in mitochondrion. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO14053 | SLC25A45 Knockout cell line (HeLa) | Human | SLC25A45 | 1:3~1:6 | Negative | Online Inquiry |
KO14054 | SLC25A45 Knockout cell line (HCT 116) | Human | SLC25A45 | 1:2~1:4 | Negative | Online Inquiry |
KO14055 | SLC25A45 Knockout cell line (HEK293) | Human | SLC25A45 | 1:3~1:6 | Negative | Online Inquiry |
KO14056 | SLC25A45 Knockout cell line (A549) | Human | SLC25A45 | 1:3~1:4 | Negative | Online Inquiry |
SLC25A45 Gene Knockout Cell Lines are genetically engineered cell lines that have been specifically designed to lack the SLC25A45 gene, a crucial component involved in mitochondrial transport mechanisms. By removing this gene, researchers can investigate the functional implications of SLC25A45 in various biological pathways, particularly those related to mitochondrial dynamics, energy metabolism, and cellular stress responses.
The primary function of the SLC25A45 gene is to encode a protein that facilitates the transport of specific metabolites across the inner mitochondrial membrane, playing a vital role in maintaining mitochondrial and cellular homeostasis. The knockout of this gene allows scientists to explore its role in metabolic conditions and to assess the changes in energy production and reactive oxygen species (ROS) generation in response to varying physiological conditions.
This product holds significant scientific importance as mitochondria are central to cellular energy metabolism and play a vital role in numerous diseases, including metabolic disorders, neurodegeneration, and cancer. By utilizing SLC25A45 Knockout Cell Lines, researchers can gain insights into disease mechanisms, evaluate potential therapeutic targets, and develop innovative treatment strategies. These cell lines are particularly valuable in drug discovery and preclinical studies, providing a robust model for screening compounds that may modulate mitochondrial function.
What sets SLC25A45 Gene Knockout Cell Lines apart from alternative cell models is their highly specific genetic modification that directly facilitates the study of the SLC25A45 pathway without the confounding factors associated with wild-type cell lines. This specificity enhances the reliability of experimental outcomes and allows for more precise data interpretation.
Researchers and clinicians will find high value in the capabilities of SLC25A45 Knockout Cell Lines to elucidate critical pathways that inform both basic and translational research in mitochondrial biology and associated diseases. Our company brings extensive expertise in genetic engineering and offers a diverse range of biological products designed to empower researchers in their quests for scientific advancement.
Please note that all services are for research use only. Not intended for any clinical use.
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