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SLC16A7 Knockout Cell Lines

Gene: SLC16A7

Official Full Name: solute carrier family 16 member 7provided by HGNC

Gene Summary: This gene is a member of the monocarboxylate transporter family. Members in this family transport metabolites, such as lactate, pyruvate, and ketone bodies. The protein encoded by this gene catalyzes the proton-linked transport of monocarboxylates and has the highest affinity for pyruvate. This protein has been reported to be more highly expressed in prostate and colorectal cancer specimens when compared to control specimens. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO33489 SLC16A7 Knockout cell line (HeLa) Human SLC16A7 1:3~1:6 Negative Online Inquiry
KO33490 SLC16A7 Knockout cell line (HCT 116) Human SLC16A7 1:2~1:4 Negative Online Inquiry

Background

SLC16A7 Gene Knockout Cell Lines represent a specialized tool in molecular biology aimed at elucidating the functions associated with the SLC16A7 gene, which encodes for a member of the solute carrier family of transporters. These cell lines are engineered through advanced CRISPR/Cas9 technology, where the SLC16A7 gene has been deliberately disrupted to facilitate the study of its biological roles and associated metabolic pathways. The knockout functionality allows researchers to investigate the phenotype resulting from the absence of this transporter, which is implicated in various physiological and pathological processes.

The primary mechanism of SLC16A7 involves the transport of lactate and other monocarboxylates across cellular membranes, a critical process in cellular metabolism and energy homeostasis. By utilizing knockout models, researchers can decipher the biological impact of SLC16A7, including its potential contributions to metabolic disorders, cancer metabolism, and neuronal signaling. Importantly, these cell lines can be used in various experimental assays to probe cellular responses under different conditions, providing insights into therapeutic targets for related diseases.

SLC16A7 Gene Knockout Cell Lines offer distinct advantages over wild-type or alternative models. The controlled genetic background minimizes variability in experimental outcomes, facilitating more reproducible findings. Additionally, these knockout lines create a robust platform for high-throughput screening of compounds that may modulate SLC16A7 activity, supporting drug discovery efforts and enabling the identification of novel therapeutic strategies.

Investing in SLC16A7 Gene Knockout Cell Lines is invaluable for researchers focused on metabolic regulation, therapeutic interventions, and understanding gene function in health and disease. With an increasing emphasis on personalized medicine, the ability to study genetic variations with precision becomes crucial in clinical and translational research settings.

Our company prides itself on delivering high-quality biological products backed by extensive expertise in gene knockout technologies and a commitment to advancing the field of molecular biology. By providing cutting-edge tools such as SLC16A7 Gene Knockout Cell Lines, we aim to empower researchers and clinicians in their quest to unravel the complexities of gene function and its implications in health and disease.

Please note that all services are for research use only. Not intended for any clinical use.

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