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SLC15A3 Knockout Cell Lines

Gene: SLC15A3

Official Full Name: solute carrier family 15 member 3provided by HGNC

Gene Summary: Enables dipeptide transmembrane transporter activity. Involved in dipeptide import across plasma membrane. Located in intracellular membrane-bounded organelle. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO00055 SLC15A3 Knockout cell line (HeLa) Human SLC15A3 1:3~1:6 Negative Online Inquiry

Background

SLC15A3 Gene Knockout Cell Lines represent a cutting-edge platform utilized in molecular biology for the study of the SLC15A3 gene, which encodes a proton-coupled oligopeptide transporter. Employing CRISPR-Cas9 genome editing technology, these knockout cell lines are designed to facilitate the quantitative analysis of cellular processes impacted by the absence of SLC15A3, an important factor in nutrient transport and drug absorption within various tissues.

The primary function of SLC15A3 is to mediate the uptake of small peptides and certain drug compounds across the cell membrane through an electrochemical gradient, which plays a crucial role in pharmacokinetics and drug efficacy. By creating knockout cell lines, researchers can delve into the physiological genes' pathways, elucidating their roles in metabolism, cell signaling, and disease mechanisms, especially in cancer and metabolic disorders.

The scientific importance of SLC15A3 knockout cell lines lies in their extensive applications in both research and clinical settings. They serve as invaluable tools for drug discovery, enabling scientists to examine how the lack of SLC15A3 activity influences drug metabolism and therapeutic outcomes. Additionally, these cell lines can be instrumental in developing personalized medicine strategies, allowing for tailored therapeutic approaches based on individual genetic profiles.

What sets our SLC15A3 Gene Knockout Cell Lines apart from alternatives is their high specificity and efficiency, supported by rigorous quality control measures. These cell lines are validated to ensure consistent performance, reducing variability in experimental results while providing researchers with a reliable model for studying gene function.

This product is of paramount value to researchers, clinicians, and pharmacologists who seek to enhance their understanding of nutrient transport mechanisms and improve drug delivery systems. The insights gained from using these knockout cell lines can potentially lead to breakthroughs in treatment modalities and contribute to advancements in biopharmaceuticals.

Our company is dedicated to advancing scientific research and innovation. With a strong emphasis on quality and reproducibility, we provide researchers with the tools necessary to push the boundaries of biological science, promoting deeper insights and fostering discovery in the fields of genomics and pharmacology.

Please note that all services are for research use only. Not intended for any clinical use.

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