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SHROOM3 Knockout Cell Lines

Gene: SHROOM3

Official Full Name: shroom family member 3provided by HGNC

Gene Summary: This gene encodes a PDZ-domain-containing protein that belongs to a family of Shroom-related proteins. This protein may be involved in regulating cell shape in certain tissues. A similar protein in mice is required for proper neurulation. [provided by RefSeq, Jan 2011]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO14151 SHROOM3 Knockout cell line (HeLa) Human SHROOM3 1:3~1:6 Negative Online Inquiry
KO14152 SHROOM3 Knockout cell line (HCT 116) Human SHROOM3 1:2~1:4 Negative Online Inquiry
KO14153 SHROOM3 Knockout cell line (HEK293) Human SHROOM3 1:3~1:6 Negative Online Inquiry
KO14154 SHROOM3 Knockout cell line (A549) Human SHROOM3 1:3~1:4 Negative Online Inquiry

Background

SHROOM3 Gene Knockout Cell Lines are specialized cell cultures in which the SHROOM3 gene has been systematically inactivated, enabling researchers to study the specific functions and regulatory pathways associated with this important gene. SHROOM3 is known to play a crucial role in cellular adhesion, morphology, and migration, particularly in the context of neural and epithelial development. By utilizing these knockout cell lines, investigators can delve deeper into the biological implications of SHROOM3 loss, shedding light on its involvement in various physiological processes and disease states.

The key mechanisms of action involve the elimination of SHROOM3-dependent pathways, allowing for the observation of altered cellular behavior, signaling cascades, and gene expression profiles. This information is vital for elucidating the gene’s role in diseases such as autism spectrum disorders, cardiovascular disease, and certain cancers, where aberrant cell signaling can drive pathology. The SHROOM3 Gene Knockout Cell Lines serve as an effective model system to assess phenotypic variations, explore compensatory mechanisms, and validate targeted therapeutic strategies.

In research and clinical settings, the scientific importance of these cell lines is underscored by their relevance in understanding disease mechanisms and developing novel interventions. Unlike conventional cell lines, SHROOM3 knockout lines offer a unique platform for studying gene function in a controlled environment, reducing variability introduced by other genetic factors.

One significant advantage of SHROOM3 Gene Knockout Cell Lines is their customization and validation, ensuring that they meet the specific needs of diverse research projects. They provide a reliable tool for drug development and testing, enhancing the precision of preclinical models and yielding more robust data for downstream applications.

For researchers, clinicians, and pharmaceutical developers, capitalizing on the insights gained from SHROOM3 Gene Knockout Cell Lines can lead to better therapeutic strategies and innovations in disease treatment. Our commitment to delivering high-quality, validated biological products ensures that our offerings facilitate cutting-edge research and contribute to advancing scientific knowledge, ultimately benefiting society at large through a deeper understanding of genetic regulation and its complications.

Please note that all services are for research use only. Not intended for any clinical use.

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