Home / SHPK Knockout Cell Lines

SHPK Knockout Cell Lines

Gene: SHPK

Official Full Name: sedoheptulokinaseprovided by HGNC

Gene Summary: The protein encoded by this gene has weak homology to several carbohydrate kinases, a class of proteins involved in the phosphorylation of sugars as they enter a cell, inhibiting return across the cell membrane. Sequence variation between this novel gene and known carbohydrate kinases suggests the possibility of a different substrate, cofactor or changes in kinetic properties distinguishing it from other carbohydrate kinases. The gene resides in a region commonly deleted in cystinosis patients, suggesting a role as a modifier for the cystinosis phenotype. The genomic region is also rich in Alu repetitive sequences, frequently involved in chromosomal rearrangements. [provided by RefSeq, Jul 2008]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO04791 SHPK Knockout cell line (HeLa) Human SHPK 1:3~1:6 Negative Online Inquiry
KO04792 SHPK Knockout cell line (HCT 116) Human SHPK 1:2~1:4 Negative Online Inquiry
KO04793 SHPK Knockout cell line (HEK293) Human SHPK 1:3~1:6 Negative Online Inquiry
KO04794 SHPK Knockout cell line (A549) Human SHPK 1:3~1:4 Negative Online Inquiry

Background

SHPK Gene Knockout Cell Lines are specialized cellular models engineered to exhibit the complete disruption of the SHPK (sulfhydration of phosphoenolpyruvate carboxykinase) gene. This gene is implicated in various biochemical pathways related to energy metabolism and cellular signaling, making these knockout cell lines invaluable tools for researchers and clinicians studying the physiological and pathological implications of SHPK deficiency.

The primary function of SHPK Gene Knockout Cell Lines lies in their ability to facilitate detailed investigations into the role of the SHPK gene in metabolic processes. By preventing the expression of this specific gene, these cell lines enable researchers to elucidate the impact of SHPK on cellular functions such as glucose metabolism, nucleotide synthesis, and response to hypoxia. This knockout model serves as a powerful platform for testing therapeutic interventions and understanding disease mechanisms associated with metabolic disorders and certain cancers.

Scientifically, SHPK Gene Knockout Cell Lines are crucial for both basic research and clinical applications. They provide a framework for unraveling the complexities of metabolic regulation and the consequences of SHPK deficiencies, advancing our understanding of disorders such as diabetes and cancer. Their use in preclinical studies can aid in the development of targeted therapies, enhancing our ability to combat these prevalent health issues effectively.

Compared to traditional cell lines, SHPK Gene Knockout Cell Lines offer a distinct advantage by eliminating the variable of SHPK expression, thus providing a more controlled environment for experimental procedures. This specificity facilitates reproducibility and enhances the reliability of data, making them a superior choice for investigators focused on metabolic research.

For researchers, clinicians, and biotechnology enterprises alike, the ability to manipulate gene function in real time unlocks new possibilities for discovery and innovation. The SHPK Gene Knockout Cell Lines represent the forefront of cell biology research, allowing for in-depth mechanistic studies and therapeutic advancements.

With a commitment to excellence, our company specializes in providing high-quality cellular models and biological products, backed by robust scientific expertise. We ensure our offerings meet the highest standards of accuracy and reliability, empowering your research and clinical goals.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.