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SHISA4 Knockout Cell Lines

Gene: SHISA4

Official Full Name: shisa family member 4provided by HGNC

Gene Summary: Predicted to be located in membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO22572 SHISA4 Knockout cell line (HeLa) Human SHISA4 1:3~1:6 Negative Online Inquiry
KO22573 SHISA4 Knockout cell line (HCT 116) Human SHISA4 1:2~1:4 Negative Online Inquiry
KO22574 SHISA4 Knockout cell line (A549) Human SHISA4 1:3~1:4 Negative Online Inquiry

Background

SHISA4 Gene Knockout Cell Lines are genetically engineered cell lines designed for targeted investigations into the function of the SHISA4 gene, which plays a pivotal role in synaptic transmission and neuronal development. By utilizing CRISPR-Cas9 technology, these cell lines provide a reliable platform for studying the molecular pathways influenced by SHISA4, offering insights into neurological disorders and synaptic dysfunctions.

The primary mechanism of action involves the precise deletion of the SHISA4 gene, allowing researchers to observe resultant phenotypic changes and alterations in signaling pathways. Inhibition studies and rescue experiments with the SHISA4 knockouts enable scientists to dissect the gene's role in synaptic plasticity and its implications in diseases such as epilepsy and cognitive impairments. The SHISA4 Gene Knockout Cell Lines thus serve as a powerful tool in elucidating complex neurobiological processes.

The scientific significance of these cell lines is underscored by their potential applications in drug discovery, genetic research, and therapeutic development. By understanding the functional consequences of SHISA4 gene knockout, researchers can identify novel targets for intervention in neurological diseases, making these cell lines invaluable for both academic and clinical research settings.

Compared to alternative models, such as traditional knockout mice, the SHISA4 Gene Knockout Cell Lines offer rapid experimental turnaround, reduced costs, and high-throughput screening capabilities, enabling more efficient exploration of gene function. Additionally, these cell lines are ready-to-use, saving researchers valuable time in generating their own models.

As a trusted provider of advanced genetic tools, our company brings extensive expertise in developing and characterizing knockout cell lines. By choosing SHISA4 Gene Knockout Cell Lines, researchers gain access to a robust platform that accelerates the understanding of neuronal biology while paving the way for advancements in therapeutic applications.

Please note that all services are for research use only. Not intended for any clinical use.

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