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SHF Knockout Cell Lines

Gene: SHF

Official Full Name: Src homology 2 domain containing Fprovided by HGNC

Gene Summary: Predicted to enable phosphotyrosine residue binding activity. Predicted to be involved in apoptotic process. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO23720 SHF Knockout cell line (HeLa) Human SHF 1:3~1:6 Negative Online Inquiry
KO23721 SHF Knockout cell line (HCT 116) Human SHF 1:2~1:4 Negative Online Inquiry
KO23722 SHF Knockout cell line (HEK293) Human SHF 1:3~1:6 Negative Online Inquiry
KO23723 SHF Knockout cell line (A549) Human SHF 1:3~1:4 Negative Online Inquiry

Background

SHF Gene Knockout Cell Lines are highly specialized cellular models engineered to facilitate the targeted disruption of the SHF (spleen focus-forming virus integration 1) gene. These cell lines are crucial tools in the study of gene function and regulation, allowing researchers to systematically investigate the role of SHF in various biological processes such as cell signaling, differentiation, and oncogenesis. The knockout mechanism relies on CRISPR-Cas9 technology, which enables precise editing of the genome by creating double-strand breaks at the designated SHF gene locus, followed by erroneous repair that leads to the loss of gene function.

The scientific significance of SHF Gene Knockout Cell Lines lies in their ability to accelerate research in both basic biology and clinical applications. By removing the SHF gene, scientists can elucidate its contributions to cellular behavior and disease mechanisms, particularly in the context of cancer and developmental disorders. In therapeutic settings, these cell lines can also serve as valuable models for drug screening and testing the effects of potential therapeutic agents targeting SHF-related pathways.

A key advantage of our SHF Gene Knockout Cell Lines is their proven reliability and reproducibility, setting them apart from traditional knockout models which may exhibit variability. Additionally, their ease of use and the comprehensive characterizations provided enable researchers to obtain robust data quickly. This ensures that users can carry out experiments with confidence, translating findings into actionable insights efficiently.

For researchers and clinicians looking to deepen their understanding of SHF function or develop innovative therapeutic strategies, these cell lines represent a significant resource. Our commitment to quality and scientific integrity is backed by years of expertise in cellular biology, making our product not only a reliable choice but also an essential addition to the toolkits of scientists worldwide. Our comprehensive offerings are designed to support advancement in life science research and clinical applications, positioning us as a leader in the field.

Please note that all services are for research use only. Not intended for any clinical use.

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