Gene: SH3RF3
Official Full Name: SH3 domain containing ring finger 3provided by HGNC
Gene Summary: Enables ubiquitin protein ligase activity. Involved in positive regulation of JNK cascade and protein autoubiquitination. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO20800 | SH3RF3 Knockout cell line (HEK293) | Human | SH3RF3 | 1:3~1:6 | Negative | Online Inquiry |
SH3RF3 Gene Knockout Cell Lines represent a cutting-edge tool in genetic research, designed to facilitate the investigation of the biological functions and physiological roles of the SH3RF3 gene. These engineered cell lines have been meticulously crafted using advanced CRISPR-Cas9 technology, resulting in precise and efficient deletion of the SH3RF3 gene, allowing for the study of its implications in cellular processes such as growth, differentiation, and apoptosis.
The primary function of the SH3RF3 Gene Knockout Cell Lines is to provide researchers with a stable model system to probe the gene’s contributions to various signaling pathways and disease states, particularly in cancer and metabolic disorders. The knockout of SH3RF3 permits scientists to analyze gene interactions, downstream effects, and compensatory mechanisms within cellular contexts, promoting a deeper understanding of its role in health and disease.
The scientific importance of these cell lines extends to both academic research and clinical exploration. They offer essential insights into the potential targeting of SH3RF3-related pathways for therapeutic intervention. For example, insights gained from using these cell lines can facilitate the development of novel biomarkers or therapeutic agents, making them invaluable in drug discovery processes.
In comparison to other available models, the SH3RF3 Gene Knockout Cell Lines boast enhanced specificity and reproducibility due to the definitive nature of CRISPR-mediated gene knockout. This specificity not only reduces off-target effects but also ensures that resulting phenotypes can be directly attributed to the loss of SH3RF3 function, a significant advantage over traditional RNAi techniques.
The value of SH3RF3 Gene Knockout Cell Lines to researchers and clinicians lies in their ability to advance scientific knowledge and therapeutic development through meticulous genetic exploration. By providing an accessible and effective means to manipulate the SH3RF3 gene, these cell lines empower users to draw meaningful conclusions about gene function, enrich our understanding of biological systems, and ultimately drive innovation in the healthcare sector.
Our company prides itself on its expertise in generating high-quality biological tools tailored for the scientific community, ensuring researchers have access to reliable products that enhance their work while upholding the highest standards of scientific rigor.
Please note that all services are for research use only. Not intended for any clinical use.
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