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SH3BP5 Knockout Cell Lines

Gene: SH3BP5

Official Full Name: SH3 domain binding protein 5provided by HGNC

Gene Summary: Enables guanyl-nucleotide exchange factor activity and protein kinase inhibitor activity. Acts upstream of or within intracellular signal transduction. Located in cytoplasmic vesicle membrane and nuclear body. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO05150 SH3BP5 Knockout cell line (HeLa) Human SH3BP5 1:3~1:6 Negative Online Inquiry
KO05151 SH3BP5 Knockout cell line (HCT 116) Human SH3BP5 1:2~1:4 Negative Online Inquiry
KO05152 SH3BP5 Knockout cell line (HEK293) Human SH3BP5 1:3~1:6 Negative Online Inquiry
KO05153 SH3BP5 Knockout cell line (A549) Human SH3BP5 1:3~1:4 Negative Online Inquiry

Background

SH3BP5 Gene Knockout Cell Lines are genetically engineered mammalian cell lines that have been designed to specifically lack the SH3BP5 gene, which codifies for the SH3-domain binding protein 5. This gene plays a crucial role in various cellular processes, including signal transduction and endocytosis, making it essential for the normal function of immune responses and cellular homeostasis. The mechanism of action involves the ablation of the SH3BP5 protein, which facilitates the study of gene function and the molecular pathways in which it participates.

The scientific importance of SH3BP5 Gene Knockout Cell Lines is underscored by their applications in both fundamental research and clinical settings. Researchers can utilize these cell lines to investigate the signaling pathways regulated by SH3BP5, enabling the exploration of its role in disease mechanisms, particularly those related to immunological disorders and cancer. Furthermore, these knockout models may serve as invaluable tools for drug discovery and development, as they allow for the testing of therapeutic compounds that target the cellular machinery modulated by SH3BP5.

In comparison to other traditional cell models, the SH3BP5 Gene Knockout Cell Lines offer several unique advantages. They provide a clean genetic background devoid of the confounding effects of the SH3BP5 gene, facilitating clearer interpretations of experimental results. Additionally, our cell lines are validated for consistent performance and can be easily cultured, allowing for straightforward integration into existing laboratory workflows.

Researchers and clinicians will find significant value in these cell lines as they present an opportunity to elucidate molecular mechanisms and potentially identify novel therapeutic targets. By leveraging our deep expertise in genetic engineering and cell culture techniques, we ensure that the SH3BP5 Gene Knockout Cell Lines are of the highest quality, tailored for effective research outcomes. Our commitment to advancing scientific discovery strengthens the foundations upon which your research can thrive.

Please note that all services are for research use only. Not intended for any clinical use.

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