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SGTB Knockout Cell Lines

Gene: SGTB

Official Full Name: small glutamine rich tetratricopeptide repeat co-chaperone betaprovided by HGNC

Gene Summary: Predicted to enable molecular adaptor activity. Predicted to be involved in post-translational protein targeting to endoplasmic reticulum membrane. Predicted to be part of TRC complex. Predicted to be active in membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO21615 SGTB Knockout cell line (HeLa) Human SGTB 1:3~1:6 Negative Online Inquiry
KO21616 SGTB Knockout cell line (HCT 116) Human SGTB 1:2~1:4 Negative Online Inquiry
KO21617 SGTB Knockout cell line (HEK293) Human SGTB 1:3~1:6 Negative Online Inquiry
KO21618 SGTB Knockout cell line (A549) Human SGTB 1:3~1:4 Negative Online Inquiry

Background

SGTB Gene Knockout Cell Lines are specialized cellular models engineered to lack the SGTB gene, which encodes for a protein implicated in various cellular processes such as protein degradation and cellular response to stress. By employing CRISPR-Cas9 technology, these cell lines are meticulously crafted to facilitate the study of gene function and its implications in both normal physiology and disease states. The specific mechanism of action allows researchers to observe the phenotypic and functional changes that arise from the complete absence of SGTB, providing insights into its role in cellular mechanisms.

In research and clinical settings, these knockout cell lines are invaluable for elucidating gene functions, validating drug targets, and understanding disease mechanisms, particularly in cancer and neurodegenerative disorders where SGTB may play a pivotal role. They serve as robust platforms for screening potential therapeutic compounds and for conducting mechanistic studies that can ultimately lead to the development of novel interventions.

The SGTB Gene Knockout Cell Lines stand out due to their high specificity and the reliability of CRISPR technology, offering precision that other gene-editing methods may lack. Unlike traditional methods such as RNA interference, knockout strategies provide a more permanent and stable model, allowing for reproducibility in experiments over extended periods. This uniqueness positions our product as an essential tool for both academic research and biopharmaceutical development.

Given the increasing demand for precise genetic models in biological research, SGTB Gene Knockout Cell Lines offer an efficient, cost-effective solution for researchers aiming to advance their studies. Our firm has extensive experience in developing cutting-edge biological products, ensuring that our offerings are backed by rigorous scientific validation and designed to support the evolving needs of the research community.

Please note that all services are for research use only. Not intended for any clinical use.

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