Gene: SGSM3
Official Full Name: small G protein signaling modulator 3provided by HGNC
Gene Summary: Enables GTPase activator activity and small GTPase binding activity. Involved in several processes, including Rap protein signal transduction; positive regulation of GTPase activity; and regulation of Rab protein signal transduction. Located in cytosol. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO27608 | SGSM3 Knockout cell line (HeLa) | Human | SGSM3 | 1:3~1:6 | Negative | Online Inquiry |
KO27609 | SGSM3 Knockout cell line (HCT 116) | Human | SGSM3 | 1:2~1:4 | Negative | Online Inquiry |
KO27610 | SGSM3 Knockout cell line (HEK293) | Human | SGSM3 | 1:3~1:6 | Negative | Online Inquiry |
KO27611 | SGSM3 Knockout cell line (A549) | Human | SGSM3 | 1:3~1:4 | Negative | Online Inquiry |
SGSM3 Gene Knockout Cell Lines are specialized human cell lines engineered to eliminate the expression of the SGSM3 gene, a critical component implicated in cellular signaling pathways and disease mechanisms. This knockout technology utilizes CRISPR-Cas9 methodologies, which enables precise gene editing by inducing double-strand breaks at targeted genomic sites, followed by non-homologous end joining. The resultant cell lines not only serve as vital tools for elucidating SGSM3’s role in cellular processes but also provide a viable platform for high-throughput screening assays to identify novel therapeutic compounds.
The key function of SGSM3 is related to its involvement in the regulation of GTPases, which are integral to various cellular functions, including proliferation, differentiation, and apoptosis. By utilizing SGSM3 knockout cell lines, researchers can systematically investigate the downstream effects of SGSM3 loss, paving the way for insights into pathologies such as cancer and neurodegenerative diseases. The scientific importance of these models extends into therapeutic research, where understanding gene function can lead to targeted treatments.
Compared to other gene knockout technologies, our SGSM3 Gene Knockout Cell Lines offer unparalleled specificity and efficiency, minimizing off-target effects that often complicate genetic studies. Moreover, these cell lines come extensively validated, ensuring reproducibility in experiments and providing users with confidence in their results.
For researchers and clinicians, the value of SGSM3 Gene Knockout Cell Lines lies in their potential to accelerate scientific discovery and enhance translational research efforts. By facilitating a deeper understanding of SGSM3-related pathways, our product not only aids in the development of innovative medical therapies but also opens new avenues for the exploration of disease mechanisms.
With a commitment to advancing genetic research, our company offers state-of-the-art cellular products backed by extensive expertise in gene editing and molecular biology, positioning us as a trusted partner in your scientific endeavors.
Please note that all services are for research use only. Not intended for any clinical use.
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