Gene: SETD9
Official Full Name: SET domain containing 9provided by HGNC
Gene Summary: Predicted to enable lysine N-methyltransferase activity. Predicted to be involved in regulation of signal transduction by p53 class mediator. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO26493 | SETD9 Knockout cell line (HeLa) | Human | SETD9 | 1:3~1:6 | Negative | Online Inquiry |
KO26494 | SETD9 Knockout cell line (HCT 116) | Human | SETD9 | 1:2~1:4 | Negative | Online Inquiry |
KO26495 | SETD9 Knockout cell line (HEK293) | Human | SETD9 | 1:3~1:6 | Negative | Online Inquiry |
KO26496 | SETD9 Knockout cell line (A549) | Human | SETD9 | 1:3~1:4 | Negative | Online Inquiry |
SETD9 Gene Knockout Cell Lines represent a cutting-edge biological tool meticulously developed for the study of gene function and regulation, specifically targeting the SETD9 gene, known for its role in modifying histones and influencing epigenetic regulation. These cell lines have undergone precise gene editing to create a knockout model, allowing researchers to investigate the consequences of SETD9 deficiency on cellular processes such as proliferation, differentiation, and apoptosis.
The primary mechanism of action involves the complete ablation of the SETD9 gene, thereby eliminating the SETD9 protein's involvement in methylation processes that can alter chromatin structure and gene expression. By utilizing these knockout cell lines, researchers can elucidate the downstream pathways affected by the loss of SETD9, paving the way for a better understanding of its contribution to various diseases, including cancer and neurodegenerative disorders.
The scientific importance of SETD9 Gene Knockout Cell Lines is underscored by their applicability in both basic and translational research settings. They provide a valuable platform for drug discovery, genetic screening, and therapeutic development. Additionally, they enable the contextualization of findings within the broader field of epigenetics, an area increasingly recognized for its relevance in cellular dynamics and disease pathology.
What sets our SETD9 Gene Knockout Cell Lines apart from alternative models is their high specificity and reliability. Each line is validated to ensure consistent gene knockout efficiency and cellular behavior, reducing experimental variability. Furthermore, our lines are optimized for a variety of culture conditions and assays, making them accessible for diverse research needs.
For researchers, clinicians, and biotechnology firms, these knockout cell lines present an invaluable resource for uncovering novel insights into gene function and its implications in health and disease. Their use will not only enhance foundational knowledge but also facilitate the development of innovative therapeutic strategies.
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Please note that all services are for research use only. Not intended for any clinical use.
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