Gene: SESN2
Official Full Name: sestrin 2provided by HGNC
Gene Summary: This gene encodes a member of the sestrin family of PA26-related proteins. The encoded protein may function in the regulation of cell growth and survival. This protein may be involved in cellular response to different stress conditions. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO09202 | SESN2 Knockout cell line (HeLa) | Human | SESN2 | 1:3~1:6 | Negative | Online Inquiry |
KO09203 | SESN2 Knockout cell line (HCT 116) | Human | SESN2 | 1:2~1:4 | Negative | Online Inquiry |
KO09204 | SESN2 Knockout cell line (HEK293) | Human | SESN2 | 1:3~1:6 | Negative | Online Inquiry |
KO09205 | SESN2 Knockout cell line (A549) | Human | SESN2 | 1:3~1:4 | Negative | Online Inquiry |
SESN2 Gene Knockout Cell Lines are advanced biological tools designed to facilitate the study of the Sesn2 gene's role in cellular processes such as metabolism, stress response, and aging. By employing CRISPR/Cas9 gene-editing technology, these cell lines have had the SESN2 gene specifically inactivated, enabling researchers to investigate the functional consequences of its absence in various cellular contexts.
The key function of SESN2, also known as sestrin 2, revolves around its involvement in the activation of autophagy, the modulation of oxidative stress, and the regulation of the insulin signaling pathway. SESN2 plays a crucial role in enhancing cellular resilience against metabolic stress, making its knockout invaluable for exploring the gene's influence in pathways associated with age-related diseases, cancer, and metabolic disorders. In research, SESN2 knockout cell lines provide a powerful platform for dissecting the molecular mechanisms by which cells adapt to physiological challenges, illuminating potential therapeutic targets for painful conditions like neurodegeneration or metabolic syndrome.
What sets our SESN2 Gene Knockout Cell Lines apart from alternatives is the rigorous validation process they undergo, ensuring that the knockout is complete and reliable. Moreover, these cell lines are developed from widely used backgrounds, allowing for straightforward integration into existing research paradigms. Their versatility supports myriad applications, from basic molecular biology studies to drug discovery.
Researchers and clinicians can leverage these knockout models to conduct highly reproducible experiments, thereby generating data critical for advancing scientific understanding and therapeutic strategies. Our expertise in producing high-quality genetic models positions us as a leader in the field, ensuring that our clients receive not only the products but also the consistent support needed for impactful research. Engaging with SESN2 Gene Knockout Cell Lines can significantly enhance your research capabilities, paving the way for new insights into cellular homeostasis and disease mechanisms.
Please note that all services are for research use only. Not intended for any clinical use.
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