Gene: SERTAD3
Official Full Name: SERTA domain containing 3provided by HGNC
Gene Summary: The protein encoded by this gene was identified in a yeast two-hybrid assay employing the second subunit of human replication protein A as bait. It is localized to the nucleus and its expression is significantly higher in cancer cell lines compared to normal cell lines. This protein has also been shown to be a strong transcriptional co-activator. Alternative splicing has been observed at this locus and two variants, both encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO05322 | SERTAD3 Knockout cell line (HeLa) | Human | SERTAD3 | 1:3~1:6 | Negative | Online Inquiry |
KO05323 | SERTAD3 Knockout cell line (HCT 116) | Human | SERTAD3 | 1:2~1:4 | Negative | Online Inquiry |
KO05324 | SERTAD3 Knockout cell line (HEK293) | Human | SERTAD3 | 1:3~1:6 | Negative | Online Inquiry |
KO05325 | SERTAD3 Knockout cell line (A549) | Human | SERTAD3 | 1:3~1:4 | Negative | Online Inquiry |
SERTAD3 Gene Knockout Cell Lines are genetically modified cell systems designed to lack the expression of the SERTAD3 gene, a critical player in various cellular processes, including cell proliferation and cancer progression. These well-characterized knockout cell lines utilize CRISPR-Cas9 technology, ensuring precise edits to the genome, which in turn facilitates comprehensive studies of SERTAD3’s biological roles and its implications in disease mechanisms.
The key functions of SERTAD3 encompass regulation of transcription and involvement in the modulation of signaling pathways that are pivotal in cellular growth and differentiation. By studying these knockout cell lines, researchers can elucidate the contributions of SERTAD3 to processes such as malignant transformation, neurogenesis, and tissue homeostasis. Through this, scientists are equipped to explore potential therapeutic targets for various disorders, including cancer and neurodegenerative diseases.
Scientific importance lies in the necessity for reliable models to study gene function and therapeutic strategies, particularly in understanding the contributions of specific genes to pathophysiological conditions. SERTAD3 Gene Knockout Cell Lines serve as invaluable tools in both academic and clinical research settings, enabling the elucidation of complex biological phenomena associated with SERTAD3.
Compared to traditional cell lines, our knockout cell lines offer completeness in the knockout process, ensuring that researchers can trust the integrity of their experimental outcomes. Unlike competitors’ products, which may provide incomplete or non-specific gene modification, our cell lines are validated for SERTAD3 deletion, allowing for robust data collection with minimal confounding factors.
For researchers and clinicians, the value of SERTAD3 Gene Knockout Cell Lines is amplified through their potential to drive discoveries that translate into clinical applications, ranging from novel drug development to biomarker identification. Our company prides itself on a strong foundation of expertise in genetic engineering and cell culture technologies, ensuring that our customers receive high-quality products designed to advance their research objectives.
Please note that all services are for research use only. Not intended for any clinical use.
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