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SERPINB7 Knockout Cell Lines

Gene: SERPINB7

Official Full Name: serpin family B member 7provided by HGNC

Gene Summary: This gene encodes a member of a family of proteins which function as protease inhibitors. Expression of this gene is upregulated in IgA nephropathy and mutations have been found to cause palmoplantar keratoderma, Nagashima type. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO33938 SERPINB7 Knockout cell line (A549) Human SERPINB7 1:3~1:4 Negative Online Inquiry

Background

SERPINB7 Gene Knockout Cell Lines are advanced biological models developed to investigate the functional role of the SERPINB7 gene, which encodes a serine protease inhibitor implicated in various physiological and pathological processes, including cancer progression and inflammation. These cell lines are engineered to have the SERPINB7 gene selectively disrupted, allowing researchers to study the gene’s contribution to diverse cellular mechanisms and to assess the effects of its absence on cell behavior, signaling pathways, and interactions within the tumor microenvironment.

The key functionality of SERPINB7 Gene Knockout Cell Lines lies in their ability to provide a controlled platform for exploring the downstream effects of SERPINB7 loss. By utilizing CRISPR/Cas9 genome editing technology, these knockout cells present precise and reproducible gene modifications. This enables researchers to analyze changes in protease activity, cytokine secretion, and overall cell viability, thereby enhancing the understanding of how SERPINB7 influences physiological processes such as immune response regulation and tumorigenicity.

From a scientific perspective, the significance of these cell lines cannot be overstated. They serve as critical tools in both basic research and translational medicine, allowing for the investigation of potential therapeutic targets and the efficacy of new treatment strategies across various diseases. The SERPINB7 knockout model particularly aids in the elucidation of cancer biology, immune system interactions, and disease mechanisms, making it an invaluable resource in oncology and immunology research.

One of the standout advantages of our SERPINB7 Gene Knockout Cell Lines compared to alternative models is their rigorously validated functionality and consistency, ensuring reliable and reproducible results. Additionally, our cell lines come with comprehensive user guidelines and technical support, facilitating seamless integration into existing research workflows.

For researchers, clinicians, and pharmaceutical developers alike, these knockout cell lines represent an essential tool to drive innovation and discovery in the biomedical field. Understanding the implications of SERPINB7 can lead to breakthroughs in therapeutic interventions and biomarker development for diseases where its dysregulation has been observed.

Leveraging our company’s expertise in genetic engineering and cell culture technology, we are committed to providing high-quality biological products that empower the scientific community to advance understanding in health and disease.

Please note that all services are for research use only. Not intended for any clinical use.

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