Gene: SEPTIN8
Official Full Name: septin 8provided by HGNC
Gene Summary: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO29761 | SEPTIN8 Knockout cell line (HeLa) | Human | SEPTIN8 | 1:3~1:6 | Negative | Online Inquiry |
KO29762 | SEPTIN8 Knockout cell line (HCT 116) | Human | SEPTIN8 | 1:2~1:4 | Negative | Online Inquiry |
KO29763 | SEPTIN8 Knockout cell line (HEK293) | Human | SEPTIN8 | 1:3~1:6 | Negative | Online Inquiry |
KO29764 | SEPTIN8 Knockout cell line (A549) | Human | SEPTIN8 | 1:3~1:4 | Negative | Online Inquiry |
SEPTIN8 Gene Knockout Cell Lines are genetically engineered cell lines that have had the SEPTIN8 gene inactivated. Septins are a family of GTP-binding proteins that play essential roles in various cellular processes, including cytokinesis, cell division, and the organization of the cytoskeleton. By utilizing CRISPR/Cas9 technology, SEPTIN8 Gene Knockout Cell Lines provide researchers with a powerful tool to investigate the specific functions and mechanisms of SEPTIN8 in normal and pathological states.
The primary function of these cell lines is to enable the study of SEPTIN8's roles in cell cycle regulation and its potential involvement in diseases such as cancer. With the SEPTIN8 gene knocked out, researchers can analyze the consequent cellular behaviors, including alterations in cell proliferation, migration, and apoptosis. This knockdown can help elucidate the gene's contribution to cellular homeostasis and its interaction with other signaling pathways.
In research settings, SEPTIN8 Gene Knockout Cell Lines are invaluable for studying cell biology and disease mechanisms. They facilitate the exploration of new therapeutic targets and provide insights into cellular dysregulation associated with various conditions. Their importance extends to clinical applications where understanding the role of SEPTIN8 can lead to novel strategies for disease intervention.
Compared to alternative cell lines that might retain functional SEPTIN8, these knockout lines provide a clearer framework for studying its unique contributions in isolation. This specificity allows for more precise data collection and a streamlined approach to developing therapeutic strategies, thus enhancing the reliability of experimental results.
Researchers, clinicians, and biotechnology companies focused on innovative treatments will find SEPTIN8 Gene Knockout Cell Lines indispensable for advancing their studies. By employing these unique tools, they can gain a deeper understanding of cellular dynamics and molecular interactions.
Our company specializes in the development of technical solutions aimed at cutting-edge research. With expertise in gene editing technologies and an emphasis on high-quality biological products, we are dedicated to supporting the scientific community in their pursuit of knowledge and innovative therapies.
Please note that all services are for research use only. Not intended for any clinical use.
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